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LOINC Code 72160-5: Holo-transcobalamin II (S) [Moles/Vol]

72160-5 is a LOINC code used to identify Holo-transcobalamin II (S) [Moles/Vol] in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Holo-transcobalamin II. It is commonly used with the system or sample type Ser.

Reviewed by HealthAssure Clinical TeamUpdated 25 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Holo-transcobalamin II. It is commonly used with the system or sample type Ser.

When is it used?

  • Used in lab systems, EHRs, and clinical data exchange.
  • May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
  • Status: ACTIVE
  • Order vs observation: Both

What it does not mean

  • The code identifies the observation or test, not the actual result.

Key facts

Holo-transcobalamin II [Moles/volume] in Serum
Holo-transcobalamin II
The fraction of vitamin B12 bound to transcobalamin II (TC-II), normally <30% of the total, is considered the "active" fraction available to cells. There have been claims in the literature that measurement of specifically the "active" fraction is an earlier indicator of deficiency, although as of 2011 this claim is reported to be controversial (Am J Clin Nutr. 2011 Jul;94(1)348S-358S. Epub 2011 May 18).
2; Active B12; Active vitamin B12; Chemistry; Cobalamin; haptocorrin; holo-haptocorrin; holo-TC; Holo-TC-II; Holotranscobalamin; Level; Point in time; QNT; Quan; Quant; Quantitative; Random; Serum; SR; Substance concentration; TC; TC-2; TCII; TC-II; Transcobalamin; Transcobalamin 2; Vit B12; Vitamin B12

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Holo-transcobalamin II (S) [Moles/Vol]Holo-transcobalamin II [Moles/volume] in SerumHolo-TC-II Ser-sCncHolo-transcobalamin IICHEMHolo-transcobalamin II, BloodSCnc

Frequently asked questions

Code details

Code72160-5
SystemLOINC
Display nameHolo-transcobalamin II (S) [Moles/Vol]
DescriptionHolo-transcobalamin II
Short nameHolo-TC-II Ser-sCnc
ComponentHolo-transcobalamin II
PropertySCnc
TimingPt
System (specimen)Ser
ScaleQn
ClassCHEM
Example unitspmol/L
StatusACTIVE
Order/ObservationBoth

Flags

BillableNo
Valid clinical useNo

Source

SourceLOINC
Version2.82
Releasemain
First released2.42
Last changed2.42

Consumer names

Holo-transcobalamin II, Blood

Part names

Holo-transcobalamin IISCncPtSerQnSubstance ConcentrationPoint in time (spot)Serum

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

LOINC Code 72160-5 | HealthAssure