LOINCActiveBoth

LOINC Code 73810-4: CD3-CD16+CD56+HLA-DR+ (activated Natural Killer) cells/Cells.CD3-CD16+CD56+ FC (Bld)

73810-4 is a LOINC code used to identify CD3-CD16+CD56+HLA-DR+ (activated Natural Killer) cells/Cells.CD3-CD16+CD56+ FC (Bld) in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Cells.CD3-CD16+CD56+HLA-DR+/Cells.CD3-CD16+CD56+. It is commonly used with the system or sample type Bld.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Cells.CD3-CD16+CD56+HLA-DR+/Cells.CD3-CD16+CD56+. It is commonly used with the system or sample type Bld.

When is it used?

  • Used in lab systems, EHRs, and clinical data exchange.
  • May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
  • Status: ACTIVE
  • Order vs observation: Both
  • Method: Flow cytometry

What it does not mean

  • The code identifies the observation or test, not the actual result.

Key facts

  • CD3-CD16+CD56+HLA-DR+ (activated Natural Killer) cells/Cells.CD3-CD16+CD56+ in Blood by Flow cytometry (FC)
  • Cells.CD3-CD16+CD56+HLA-DR+/Cells.CD3-CD16+CD56+
  • The % activated natural killer (NK) cells can be determined by comparing the number of activated NK cells (CD3-CD16+CD56+HLA-DR+) out of 100 NK cells (CD3-CD16+CD56+). The submitter's lab uses HLA DR antibodies (HLA DR+) for late activation of NK cells within a subpopulation of NK cells that lack CD3 expression (CD3-) and express CD16 and CD56 (CD16+, CD56+).
  • Blood; CD3 Cells; CD3+CD16+ Cells; CD3+CD16+CD56+ Cells; CD3-CD16+ Cells; CD3-CD16+CD56+ Cells; Cell; CELL MARKERS; Cellularity; Dynamic; FC; FCGR3A; Human Leukocyte Antigen; I3; Leu11; Leu-11; Leu11b; Leu-11B; Leu19; Leu-19; Leu4; Leu-4; Natural killer cells; NCAM; Neural cell adhesion molecule; NK; NK activated; NKH1; Number fraction; Percent; Point in time; QNT; Quan; Quant; Quantitative; Random; T3; WB; Whole blood

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

CD3-CD16+CD56+HLA-DR+ (activated Natural Killer) cells/Cells.CD3-CD16+CD56+ FC (Bld)CD3-CD16+CD56+HLA-DR+ (activated Natural Killer) cells/Cells.CD3-CD16+CD56+ in Blood by Flow cytometry (FC)NK activated/NK NFr Bld FCCells.CD3-CD16+CD56+HLA-DR+/Cells.CD3-CD16+CD56+CELLMARKCD3-CD16+CD56+HLA-DR+ (activated natural killer) cells/Cells.CD3-CD16+CD56+, BloodNFr

Frequently asked questions

Code details

Code73810-4
SystemLOINC
Display nameCD3-CD16+CD56+HLA-DR+ (activated Natural Killer) cells/Cells.CD3-CD16+CD56+ FC (Bld)
DescriptionCells.CD3-CD16+CD56+HLA-DR+/Cells.CD3-CD16+CD56+
Short nameNK activated/NK NFr Bld FC
ComponentCells.CD3-CD16+CD56+HLA-DR+/Cells.CD3-CD16+CD56+
PropertyNFr
TimingPt
System (specimen)Bld
ScaleQn
MethodFlow cytometry
ClassCELLMARK
Example units%
StatusACTIVE
Order/ObservationBoth

Flags

BillableNo
Valid clinical useNo

Source

SourceLOINC
Version2.82
Releasemain
First released2.44
Last changed2.79

Consumer names

CD3-CD16+CD56+HLA-DR+ (activated natural killer) cells/Cells.CD3-CD16+CD56+, Blood

Part names

Cells.CD3-CD16+CD56+HLA-DR+/Cells.CD3-CD16+CD56+NFrPtBldQnFlow cytometryNumber FractionPoint in time (spot)BloodFlow cytometry (FC)

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.