LOINCActiveBoth

LOINC Code 74278-3: M. tuberculosis stim IFN-g ESAT-6 Ag spot count (Bld) [#]

74278-3 is a LOINC code used to identify M. tuberculosis stim IFN-g ESAT-6 Ag spot count (Bld) [#] in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Mycobacterium tuberculosis stimulated gamma interferon.ESAT-6 Ag spot count. It is commonly used with the system or sample type Bld.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Mycobacterium tuberculosis stimulated gamma interferon.ESAT-6 Ag spot count. It is commonly used with the system or sample type Bld.

When is it used?

  • Used in lab systems, EHRs, and clinical data exchange.
  • May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
  • Status: ACTIVE
  • Order vs observation: Both

What it does not mean

  • The code identifies the observation or test, not the actual result.

Key facts

  • Mycobacterium tuberculosis stimulated gamma interferon ESAT-6 Ag spot count [#] in Blood
  • Mycobacterium tuberculosis stimulated gamma interferon.ESAT-6 Ag spot count
  • The count of spots (0 to >20) in a patient's T cells that represent IFN-γ released in response to the presence of M. tuberculosis early secretory antigenic target-6 (ESAT-6) antigens. The spot count provides a measurement of the abundance of Mycobacterium tuberculosis sensitive effector T cells in the peripheral blood. This term is based on, but not limited in use to, Oxford Immunotec's T-SPOT.TB assay, used to diagnose M. tuberculosis. T-SPOT.TB assay uses enzyme-linked immunospot (ELISPOT) methodology to enumerate M. tuberculosis-sensitized T cells by capturing interferon-gamma (IFN-y) in the vicinity of T cells in the patient's whole blood. In the T-SPOT.TB assay, the test result is positive if [ESAT-6 (Panel A) - negative control spots] and/or [CFP10 (Panel B) - negative control spots] is greater than or equal to 8 spots. The test result is negative if both [Panel A - negative control] and/or [Panel B - negative control] is less than or equal to 4 spots.
  • Acid Fast; Acid Fast Bacilli; Acid fast bacillus; AFB; Blood; Cnt; Count; ID; IFN; IGRA; Infectious Disease; InfectiousDisease; Lung; M tb; M TB IFN-g; M TB IFN-g.ESAT-6 Ag; M tuberculosis; Microbiology; Mtb; Myco; Mycobact; Mycobacterium tuberculosum; Number; Point in time; Pulmonary; Pulmonology; QNT; Quan; Quant; Quantitative; Random; Respiratory; TB; Tuberculosis; WB; Whole blood

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

M. tuberculosis stim IFN-g ESAT-6 Ag spot count (Bld) [#]Mycobacterium tuberculosis stimulated gamma interferon ESAT-6 Ag spot count [#] in BloodM TB IFN-g.ESAT-6 Ag BldMycobacterium tuberculosis stimulated gamma interferon.ESAT-6 Ag spot countMICROMycobacterium tuberculosis stimulated gamma interferon.ESAT-6 Ag spot count, BloodNum

Frequently asked questions

Code details

Code74278-3
SystemLOINC
Display nameM. tuberculosis stim IFN-g ESAT-6 Ag spot count (Bld) [#]
DescriptionMycobacterium tuberculosis stimulated gamma interferon.ESAT-6 Ag spot count
Short nameM TB IFN-g.ESAT-6 Ag Bld
ComponentMycobacterium tuberculosis stimulated gamma interferon.ESAT-6 Ag spot count
PropertyNum
TimingPt
System (specimen)Bld
ScaleQn
ClassMICRO
Example units#
StatusACTIVE
Order/ObservationBoth

Flags

BillableNo
Valid clinical useNo

Source

SourceLOINC
Version2.82
Releasemain
First released2.46
Last changed2.64

Consumer names

Mycobacterium tuberculosis stimulated gamma interferon.ESAT-6 Ag spot count, Blood

Part names

Mycobacterium tuberculosis stimulated gamma interferon.ESAT-6 Ag spot countNumPtBldQnMycobacterium tuberculosis stimulated gamma interferon ESAT-6 Ag spot countNumber (count)Point in time (spot)Blood

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.