What does this LOINC code represent?

This LOINC code identifies a lab observation, measurement, question, or clinical concept in a standardized format.

Is this enough to understand my test result?

No. The code identifies the test or observation, but the interpretation depends on the actual result, reference range, and clinical context.

LOINCActiveOrder

LOINC Code 76546-1: Breast cancer 10-year risk of distant recurrence panel Prosigna

Name: LOINC Code 76546-1: Breast cancer 10-year risk of distant recurrence panel Prosigna
Creator: HealthAssure Clinical Team
Published: 2026-05-21T08:59:56.389Z

76546-1 is a LOINC code used to identify Breast cancer 10-year risk of distant recurrence panel Prosigna in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Breast cancer 10Y risk of distant recurrence panel. It is commonly used with the system or sample type ^Patient.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Breast cancer 10Y risk of distant recurrence panel. It is commonly used with the system or sample type ^Patient.

When is it used?

Used in lab systems, EHRs, and clinical data exchange.
May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
Status: ACTIVE
Order vs observation: Order
Panel type: Panel
Method: Prosigna

What it does not mean

The code identifies the observation or test, not the actual result.

Key facts

Breast cancer 10-year risk of distant recurrence panel by Prosigna

Breast cancer 10Y risk of distant recurrence panel

A 10-year breast cancer distant recurrence risk panel created for the Prosigna™ Breast Cancer Prognostic Gene Signature assay, which is intended for use in postmenopausal women with node-negative (Stage I or II) or node-positive (Stage II), hormone receptor-positive (HR+) breast cancer who have undergone surgery and are to be treated with adjuvant endocrine therapy alone. The panel includes terms for primary tumor size, lymph node status, distant recurrence risk score, and distance recurrence risk classification. The 10-year breast cancer distant recurrence risk score (also referred to as ROR Score or Risk of Recurrence Score) is a numerical score on a scale of 0 -100 that is calculated using a statistical model that includes1) the results from a 50-gene expression assay performed on formalin fixed paraffin embedded breast tumor tissue previously diagnosed as invasive carcinoma; 2) proliferation score; and 3) gross tumor size. The calculated score and information about lymph node status are used together to classify the patient into a risk category for distant breast cancer recurrence at 10 years.

breast cancer; Brst ca10Y risk dist recur Pnl; Molecular pathology; MOLPATH; PAM50; Pan; Panel.molpath; Panl; Pnl; Point in time; Prosigna; Psoriasis Care Satisfaction questionnaire; Random

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Breast cancer 10-year risk of distant recurrence panel ProsignaBreast cancer 10-year risk of distant recurrence panel by ProsignaBrst ca 10Y risk dist recur Pnl ProsignaBreast cancer 10Y risk of distant recurrence panelPANEL.MOLPATHBreast cancer 10-year risk of distant recurrence panel-

Frequently asked questions

Code details

Code76546-1

SystemLOINC

Display nameBreast cancer 10-year risk of distant recurrence panel Prosigna

DescriptionBreast cancer 10Y risk of distant recurrence panel

Short nameBrst ca 10Y risk dist recur Pnl Prosigna

ComponentBreast cancer 10Y risk of distant recurrence panel

Property-

TimingPt

System (specimen)^Patient

Scale-

MethodProsigna

ClassPANEL.MOLPATH

StatusACTIVE

Order/ObservationOrder

Flags

BillableNo

Valid clinical useNo

Source

SourceLOINC

Version2.82

Releasemain

First released2.52

Last changed2.52

Consumer names

Breast cancer 10-year risk of distant recurrence panel

Part names

Breast cancer 10Y risk of distant recurrence panel-Pt^PatientProsignaBreast cancer 10-year risk of distant recurrence panelPoint in time (spot)Psoriasis Care Satisfaction questionnaire

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.