LOINCActiveBoth

LOINC Code 82354-2: HPV 16 and 18+45 E6+E7 mRNA NAA+probe Nom (Cvx)

82354-2 is a LOINC code used to identify HPV 16 and 18+45 E6+E7 mRNA NAA+probe Nom (Cvx) in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Human papilloma virus 16 & 18+45 E6+E7 mRNA. It is commonly used with the system or sample type Cvx.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Human papilloma virus 16 & 18+45 E6+E7 mRNA. It is commonly used with the system or sample type Cvx.

When is it used?

  • Used in lab systems, EHRs, and clinical data exchange.
  • May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
  • Status: ACTIVE
  • Order vs observation: Both
  • Method: Probe.amp.tar

What it does not mean

  • The code identifies the observation or test, not the actual result.

Key facts

  • Human papilloma virus 16 and 18+45 E6+E7 mRNA [Identifier] in Cervix by NAA with probe detection
  • Human papilloma virus 16 & 18+45 E6+E7 mRNA
  • Detects E6/E7 viral messenger RNA (mRNA) of human papillomavirus (HPV) types 16, 18, and 45 in cervical specimens from women with positive HPV assay results. For women 21-years and older with atypical squamous cells of undetermined significance (ASC-US) cervical cytology results, and HPV positive assay results, this assay can be used to assess the presence or absence of high-risk HPV genotypes 16, 18, and/or 45. For women 30-years and older, the HPV 16, 18, and/or 45 genotype assay can be used to test samples from women with HPV assay positive results, along with cervical cytology results. This assay has not been evaluated for HPV vaccinated patients or in cases of suspected abuse. It differentiates HPV 16 from HPV 18 and/or HPV 45, but does not differentiate HPV 18 and HPV 45. This term was created for, but not limited in use to, the Aptima HPV 16 18/45 genotype assay which uses target capture, target amplification by transcription-mediated amplification and detection of the amplification products by hybridization protection assay (HPA).
  • 3 Self-Sustaining Sequence Replication; 3SR SR; Amplif; Amplification; Amplified; Cervix; DNA NUCLEIC ACID PROBE; DNA probe; Genital tract; Genital warts; Gyn; Gynecology; HPV; HPV 16 & 18+45; HPV16; HPV16 and 18; HPV16+18; HPV16+18+45 E6+E7mRNA; Human papillomavirus; ID; Identity or presence; Infectious Disease; InfectiousDisease; LAT; LCR; Ligase chain reaction; Ligation-activated transcription; Microbiology; NAA+probe; NAAT; NASBA; Nominal; Nucleic acid sequence based analysis; OB; ObGyn; Obstetrics; Papilloma virus high risk; PCR; Point in time; Polymerase chain reaction; Probe amp; Probe with ampification; Probe with target amplification; QBR; Random; SDA; Strand Displacement Amplification; TMA; Transcription mediated amplification

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

HPV 16 and 18+45 E6+E7 mRNA NAA+probe Nom (Cvx)Human papilloma virus 16 and 18+45 E6+E7 mRNA [Identifier] in Cervix by NAA with probe detectionHPV16+18+45 E6+E7mRNA Cvx NAA+probeHuman papilloma virus 16 & 18+45 E6+E7 mRNAMICROHPV 16 and 18+45 E6+E7 MRNA, CervixPrid

Frequently asked questions

Code details

Code82354-2
SystemLOINC
Display nameHPV 16 and 18+45 E6+E7 mRNA NAA+probe Nom (Cvx)
DescriptionHuman papilloma virus 16 & 18+45 E6+E7 mRNA
Short nameHPV16+18+45 E6+E7mRNA Cvx NAA+probe
ComponentHuman papilloma virus 16 & 18+45 E6+E7 mRNA
PropertyPrid
TimingPt
System (specimen)Cvx
ScaleNom
MethodProbe.amp.tar
ClassMICRO
StatusACTIVE
Order/ObservationBoth

Flags

BillableNo
Valid clinical useNo

Source

SourceLOINC
Version2.82
Releasemain
First released2.58
Last changed2.73

Consumer names

HPV 16 and 18+45 E6+E7 MRNA, Cervix

Part names

Human papilloma virus 16 & 18+45 E6+E7 mRNAPridPtCvxNomProbe.amp.tarHuman papilloma virus 16 and 18+45 E6+E7 mRNAPresence or IdentityPoint in time (spot)CervixNucleic acid amplification with probe detection

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

LOINC Code 82354-2 | HealthAssure