LOINC Code 82937-4: SAP and XIAP FC (WBC) [Interp]

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Signaling lymphocytic activation molecule (SLAM)-associated & X-linked inhibitor of apoptosis protein. It is commonly used with the system or sample type WBC.

When is it used?

• Used in lab systems, EHRs, and clinical data exchange.
• May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
• Status: ACTIVE
• Order vs observation: Both
• Method: Flow cytometry

What it does not mean

• The code identifies the observation or test, not the actual result.

Key facts

• SAP and XIAP [Interpretation] in Leukocytes by Flow cytometry (FC)
• Signaling lymphocytic activation molecule (SLAM)-associated & X-linked inhibitor of apoptosis protein
• Analysis of SLAM (signaling lymphocytic activation molecule)-associated protein (SAP) and X-linked inhibitor of apoptosis protein (XIAP) levels by flow cytometry is performed as a preliminary screen for X-linked lymphoproliferative (XLP) disease and X-linked familial hemophagocytic lymphohistiocytosis (HLH). If SAP protein levels are absent or decreased, XLP is suspected. If XIAP protein levels are absent or decreased, HLH (aka XLP-2) is suspected. The diagnosis is confirmed by genetic analysis of the associated genes (SH2D1A gene for XLP, BIRC4 gene for HLH).
• (SLAM)-associated protein; Assoc; BIRC4; Chemistry; Duncan disease; Dynamic; Esoteric; FC; Hemophagocytic Lymphohistiocytosis; HLH; Impression; Impression/interpretation of study; Impressions; Inhib; Inhibit; Interp; Interpretation; Leukocytes; Nominal; Point in time; PR; Prot; Purtilo syndrome; Random; SAP; SAP + XIAP; WBCs; White blood cells; XIAP; X-Linked Lymphoproliferative Disorder; XLP; XLP1; XLP2

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Frequently asked questions