LOINC Code 88459-3: Serotonin release 1.0 IU/mL heparin.low molecular weight Qn (S)

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Serotonin release 1.0 IU/mL heparin.low molecular weight. It is commonly used with the system or sample type Ser.

When is it used?

• Used in lab systems, EHRs, and clinical data exchange.
• May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
• Status: ACTIVE
• Order vs observation: Both

What it does not mean

• The code identifies the observation or test, not the actual result.

Key facts

• Serotonin release 1.0 IU/mL heparin.low molecular weight [Units/volume] in Serum
• Serotonin release 1.0 IU/mL heparin.low molecular weight
• The SRA test is a functional assay that measures heparin-dependent platelet activation. Patient serum is incubated with donor platelets containing radioactive 14C serotonin and different concentrations of heparin. Antibody present in the patient serum will bind and activate donor platelets, releasing radiolabeled serotonin from the platelet granules. A positive SRA is expected to show >20% release of the 14C serotonin when mixed with patient serum and low-dose heparin. In addition, the high-dose heparin must reduce the % release obtained with low-dose heparin by at least 50% in order to demonstrate that the platelet activation is heparin dependent.
• 5-HT; 5-hydroxytryptamine; 5-hydroxytryptophane; Arbitrary concentration; C10H12N2O; Clexane; Enoxaparin; Enteramine; Hep; Hepar; Heparin dependent platelet antibody; Heparn; HIT/HITT; LMWH; LMWH-induced thrombocytopenia; Lovenox; Point in time; QNT; Quan; Quant; Quantitative; Random; Serology; Serotonin release assay; Serum; SR; SRA; SRA 1.0 IU; SRA 1.0 IU/mL heparin; SRA 1.0 IU/mL LMW heparin; Thrombocytopenia with thrombosis syndrome; Wt

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Frequently asked questions