LOINCActiveBoth

LOINC Code 96463-5: Copper free/Total copper Calc [Mass fraction]

96463-5 is a LOINC code used to identify Copper free/Total copper Calc [Mass fraction] in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Copper.free/Copper.total. It is commonly used with the system or sample type Ser/Plas.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Copper.free/Copper.total. It is commonly used with the system or sample type Ser/Plas.

When is it used?

  • Used in lab systems, EHRs, and clinical data exchange.
  • May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
  • Status: ACTIVE
  • Order vs observation: Both
  • Method: Calculated

What it does not mean

  • The code identifies the observation or test, not the actual result.

Key facts

Copper free/Total copper in Serum or Plasma by calculation
Copper.free/Copper.total
A free copper level is calculated based on the difference between total copper and ceruloplasmin measurements, where the ceruloplasmin level represents the bound portion of circulating copper. In patients with Wilson's disease that is pre-symptomatic or adequately controlled, the free copper level is within normal range, but in symptomatic patients, it is typically elevated. Increasing free copper levels in a patient with previously normal levels may indicate a change in compliance with therapy or a growth spurt or change in diet requiring therapy adjustment. [PMID12662398] This term represents the calculated result for free copper level as a fraction of the total copper measurement.
Calc; Calculation; Copper free; Cu; DRUG/TOXICOLOGY; Drugs; FR; Mass fraction; Non-protein bound; Percent; Pl; Plasma; Plsm; Point in time; QNT; Quan; Quant; Quantitative; Random; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; Tot; Total copper; Totl

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Copper free/Total copper Calc [Mass fraction]Copper free/Total copper in Serum or Plasma by calculationCopper free/Total copper MFr SerPl CalcCopper.free/Copper.totalDRUG/TOXCopper free/Total copper, BloodMFr

Frequently asked questions

Code details

Code96463-5
SystemLOINC
Display nameCopper free/Total copper Calc [Mass fraction]
DescriptionCopper.free/Copper.total
Short nameCopper free/Total copper MFr SerPl Calc
ComponentCopper.free/Copper.total
PropertyMFr
TimingPt
System (specimen)Ser/Plas
ScaleQn
MethodCalculated
ClassDRUG/TOX
Example units%
StatusACTIVE
Order/ObservationBoth

Flags

BillableNo
Valid clinical useNo

Source

SourceLOINC
Version2.82
Releasemain
First released2.69
Last changed2.69

Consumer names

Copper free/Total copper, Blood

Part names

Copper.free/Copper.totalMFrPtSer/PlasQnCalculatedMass fractionPoint in time (spot)Serum or Plasma

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.