ICD10
ICD-10 Code A52.1: Symptomatic neurosyphilis
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 entries help standardize how diagnoses are organized for coding, reporting, analytics, and documentation. This code sits within the broader ICD-10 area for Certain infectious and parasitic diseases (A00-B99).
When is it used?
- May be used when a clinician documents symptomatic neurosyphilis in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code may act more like a grouping or parent code, so a more specific child code may be used in final documentation when available.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
- This entry may represent a broader category rather than the most specific billable code.
Code hierarchy
chapter
1Certain infectious and parasitic diseases (A00-B99)
block
A50-A64Infections with a predominantly sexual mode of transmission
category
A52Late syphilis
currentA52
Where you may see this code
You may see this entry in coding references, medical records, or claims workflows when a broader diagnosis category is being reviewed before a more specific code is chosen.
Related specialists
Infectious Disease SpecialistGeneral Physician
Related codes
A52.10Symptomatic neurosyphilis, unspecifiedcodeA52.11Tabes dorsaliscodeA52.12Other cerebrospinal syphiliscodeA52.13Late syphilitic meningitiscodeA52.14Late syphilitic encephalitiscodeA52.15Late syphilitic neuropathycodeA52.16Charcôt's arthropathy (tabetic)codeA52.17General paresiscodeA52.19Other symptomatic neurosyphiliscode
Sibling codes
Mapped diagnoses and classifications
SNOMED_CT 698725008high
Dementia associated with neurosyphilis
Source: SNOMED International ICD-10 map
SNOMED_CT 51928006high
General paresis - neurosyphilis
Source: SNOMED International ICD-10 map
SNOMED_CT 230182006high
Late syphilitic encephalitis
Source: SNOMED International ICD-10 map
SNOMED_CT 866090003high
Meningomyelitis caused by Treponema pallidum
Source: SNOMED International ICD-10 map
SNOMED_CT 240568004high
Meningovascular syphilis - quaternary stage
Source: SNOMED International ICD-10 map
SNOMED_CT 870293004high
Myelitis caused by Treponema pallidum
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy code aligns to an official FY 2026 category. Frontend should resolve to the official category page and surface the billable child codes.
Legacy codes
A52.1
Replacement codes
A52.10 — Symptomatic neurosyphilis, unspecifiedA52.11 — Tabes dorsalisA52.12 — Other cerebrospinal syphilisA52.13 — Late syphilitic meningitisA52.14 — Late syphilitic encephalitisA52.15 — Late syphilitic neuropathyA52.16 — Charcôt's arthropathy (tabetic)A52.17 — General paresisA52.19 — Other symptomatic neurosyphilis
Common synonyms
Symptomatic neurosyphilis
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.