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ICD10BillableValid for clinical use

ICD-10 Code C40.22: Malignant neoplasm of long bones of left lower limb

C40.22 is a billable ICD-10 diagnosis code used to classify Malignant neoplasm of long bones of left lower limb in medical records and claims. You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records. ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).

What is this code?

ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).

When is it used?

  • May be used when a clinician documents malignant neoplasm of long bones of left lower limb in a patient's medical record.
  • May appear in hospital records, claims, referrals, and clinical documentation.
  • This code can be used as a clinically usable diagnosis entry in standardized coding workflows.

What it does not mean

  • A code alone does not explain severity, treatment plan, or outcome.
  • A medical code should not be treated as a substitute for a doctor's diagnosis or advice.

Code hierarchy

chapter
2Neoplasms (C00-D49)
block
C00-C96Malignant neoplasms
block
C00-C75Malignant neoplasms, stated or presumed to be primary (of specified sites), and certain specified histologies, except neuroendocrine, and of lymphoid, hematopoietic and related tissue
block
C40-C41Malignant neoplasms of bone and articular cartilage
category
C40Malignant neoplasm of bone and articular cartilage of limbs
category
C40.2Malignant neoplasm of long bones of lower limb
currentC40.2

Where you may see this code

You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.

Related specialists

OncologistGeneral Physician

Coverage-related procedures and services

CPT 81479high
UNLISTED MOLECULAR PATHOLOGY PROCEDURE
Source: CMS coverage guidance
CPT 81445high
SOLID ORGAN NEOPLASM, GENOMIC SEQUENCE ANALYSIS PANEL, 5-50 GENES, INTERROGATION FOR SEQUENCE VARIANTS AND COPY NUMBER VARIANTS OR REARRANGEMENTS, IF PERFORMED; DNA ANALYSIS OR COMBINED DNA AND RNA ANALYSIS
Source: CMS coverage guidance
CPT 27130high
ARTHROPLASTY, ACETABULAR AND PROXIMAL FEMORAL PROSTHETIC REPLACEMENT (TOTAL HIP ARTHROPLASTY), WITH OR WITHOUT AUTOGRAFT OR ALLOGRAFT
Source: CMS coverage guidance
CPT 27447high
ARTHROPLASTY, KNEE, CONDYLE AND PLATEAU; MEDIAL AND LATERAL COMPARTMENTS WITH OR WITHOUT PATELLA RESURFACING (TOTAL KNEE ARTHROPLASTY)
Source: CMS coverage guidance
CPT 27132high
CONVERSION OF PREVIOUS HIP SURGERY TO TOTAL HIP ARTHROPLASTY, WITH OR WITHOUT AUTOGRAFT OR ALLOGRAFT
Source: CMS coverage guidance
CPT 0543Uhigh
ONCOLOGY (SOLID TUMOR), NEXT-GENERATION SEQUENCING OF DNA FROM FORMALIN-FIXED PARAFFIN-EMBEDDED (FFPE) TISSUE OF 517 GENES, INTERROGATION FOR SINGLE-NUCLEOTIDE VARIANTS, MULTI-NUCLEOTIDE VARIANTS, INSERTIONS AND DELETIONS FROM DNA, FUSIONS IN 24 GENES AND SPLICE VARIANTS IN 1 GENE FROM RNA, AND TUMOR MUTATION BURDEN
Source: CMS coverage guidance

Coding guidelines

Common synonyms

Malignant neoplasm of long bones of left lower limb

Frequently asked questions

Code details

CodeC40.22
SystemICD10
Display nameMalignant neoplasm of long bones of left lower limb
ChapterNeoplasms (C00-D49)
BlockMalignant neoplasms of bone and articular cartilage

Flags

BillableYes
Valid clinical useYes

Source

SourceICD-10
Version2026-annual
Releaseannual
Year2026

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.