ICD10BillableValid for clinical use
ICD-10 Code C46.9: Kaposi's sarcoma, unspecified
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).
When is it used?
- May be used when a clinician documents kaposi's sarcoma, unspecified in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code can be used as a clinically usable diagnosis entry in standardized coding workflows.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
Code hierarchy
chapter
2Neoplasms (C00-D49)
block
C00-C96Malignant neoplasms
block
C00-C75Malignant neoplasms, stated or presumed to be primary (of specified sites), and certain specified histologies, except neuroendocrine, and of lymphoid, hematopoietic and related tissue
block
C45-C49Malignant neoplasms of mesothelial and soft tissue
category
C46Kaposi's sarcoma
currentC46
Official coding notes
Inclusion terms
- Kaposi's sarcoma of unspecified site
Where you may see this code
You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.
Related specialists
OncologistGeneral Physician
Related codes
Sibling codes
Coverage-related procedures and services
CPT 81479high
UNLISTED MOLECULAR PATHOLOGY PROCEDURE
Source: CMS coverage guidance
CPT 0340Uhigh
ONCOLOGY (PAN-CANCER), ANALYSIS OF MINIMAL RESIDUAL DISEASE (MRD) FROM PLASMA, WITH ASSAYS PERSONALIZED TO EACH PATIENT BASED ON PRIOR NEXT-GENERATION SEQUENCING OF THE PATIENT'S TUMOR AND GERMLINE DNA, REPORTED AS ABSENCE OR PRESENCE OF MRD, WITH DISEASE-BURDEN CORRELATION, IF APPROPRIATE
Source: CMS coverage guidance
CPT 0422Uhigh
ONCOLOGY (PAN-SOLID TUMOR), ANALYSIS OF DNA BIOMARKER RESPONSE TO ANTI-CANCER THERAPY USING CELL-FREE CIRCULATING DNA, BIOMARKER COMPARISON TO A PREVIOUS BASELINE PRE-TREATMENT CELL-FREE CIRCULATING DNA ANALYSIS USING NEXT-GENERATION SEQUENCING, ALGORITHM REPORTED AS A QUANTITATIVE CHANGE FROM BASELINE, INCLUDING SPECIFIC ALTERATIONS, IF APPROPRIATE
Source: CMS coverage guidance
CPT 81445high
SOLID ORGAN NEOPLASM, GENOMIC SEQUENCE ANALYSIS PANEL, 5-50 GENES, INTERROGATION FOR SEQUENCE VARIANTS AND COPY NUMBER VARIANTS OR REARRANGEMENTS, IF PERFORMED; DNA ANALYSIS OR COMBINED DNA AND RNA ANALYSIS
Source: CMS coverage guidance
CPT 0569Uhigh
ONCOLOGY (SOLID TUMOR), NEXT-GENERATION SEQUENCING ANALYSIS OF TUMOR METHYLATION MARKERS (>20,000 DIFFERENTIALLY METHYLATED REGIONS) PRESENT IN CELL-FREE CIRCULATING TUMOR DNA (CTDNA), WHOLE BLOOD, ALGORITHM REPORTED AS PRESENCE OR ABSENCE OF CTDNA WITH TUMOR FRACTION, IF APPROPRIATE
Source: CMS coverage guidance
CPT 88182high
FLOW CYTOMETRY, CELL CYCLE OR DNA ANALYSIS
Source: CMS coverage guidance
Mapped diagnoses and classifications
SNOMED_CT 403979000high
Endemic Kaposi sarcoma
Source: SNOMED International ICD-10 map
SNOMED_CT 72891000119103high
Kaposi sarcoma of viscus
Source: SNOMED International ICD-10 map
SNOMED_CT 109385007high
Kaposi's sarcoma (clinical)
Source: SNOMED International ICD-10 map
SNOMED_CT 403978008high
Kaposi's sarcoma - sporadic
Source: SNOMED International ICD-10 map
SNOMED_CT 703625002high
Kaposi's sarcoma not associated with acquired immunodeficiency syndrome
Source: SNOMED International ICD-10 map
SNOMED_CT 420524008high
Kaposi's sarcoma with AIDS (acquired immunodeficiency syndrome)
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy and official ICD code match exactly.
Legacy codes
C46.9
Common synonyms
Kaposi's sarcoma, unspecifiedKaposi's sarcoma
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.