ICD10BillableValid for clinical use
ICD-10 Code C4A.9: Merkel cell carcinoma, unspecified
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).
When is it used?
- May be used when a clinician documents merkel cell carcinoma, unspecified in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code can be used as a clinically usable diagnosis entry in standardized coding workflows.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
Code hierarchy
chapter
2Neoplasms (C00-D49)
block
C00-C96Malignant neoplasms
block
C00-C75Malignant neoplasms, stated or presumed to be primary (of specified sites), and certain specified histologies, except neuroendocrine, and of lymphoid, hematopoietic and related tissue
block
C43-C44Melanoma and other malignant neoplasms of skin
category
C4AMerkel cell carcinoma
currentC4A
Official coding notes
Inclusion terms
- Merkel cell carcinoma of unspecified site
- Merkel cell carcinoma NOS
Where you may see this code
You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.
Related specialists
OncologistGeneral Physician
Related codes
C4A.0Merkel cell carcinoma of lipcodeC4A.1Merkel cell carcinoma of eyelid, including canthuscategoryC4A.2Merkel cell carcinoma of ear and external auricular canalcategoryC4A.3Merkel cell carcinoma of other and unspecified parts of facecategoryC4A.4Merkel cell carcinoma of scalp and neckcodeC4A.5Merkel cell carcinoma of trunkcategoryC4A.6Merkel cell carcinoma of upper limb, including shouldercategoryC4A.7Merkel cell carcinoma of lower limb, including hipcategoryC4A.8Merkel cell carcinoma of overlapping sitescode
Sibling codes
C4A.0Merkel cell carcinoma of lipbillableC4A.1Merkel cell carcinoma of eyelid, including canthusC4A.2Merkel cell carcinoma of ear and external auricular canalC4A.3Merkel cell carcinoma of other and unspecified parts of faceC4A.4Merkel cell carcinoma of scalp and neckbillableC4A.5Merkel cell carcinoma of trunkC4A.6Merkel cell carcinoma of upper limb, including shoulderC4A.7Merkel cell carcinoma of lower limb, including hipC4A.8Merkel cell carcinoma of overlapping sitesbillable
Coverage-related procedures and services
CPT 81479high
UNLISTED MOLECULAR PATHOLOGY PROCEDURE
Source: CMS coverage guidance
CPT 81445high
SOLID ORGAN NEOPLASM, GENOMIC SEQUENCE ANALYSIS PANEL, 5-50 GENES, INTERROGATION FOR SEQUENCE VARIANTS AND COPY NUMBER VARIANTS OR REARRANGEMENTS, IF PERFORMED; DNA ANALYSIS OR COMBINED DNA AND RNA ANALYSIS
Source: CMS coverage guidance
CPT 0543Uhigh
ONCOLOGY (SOLID TUMOR), NEXT-GENERATION SEQUENCING OF DNA FROM FORMALIN-FIXED PARAFFIN-EMBEDDED (FFPE) TISSUE OF 517 GENES, INTERROGATION FOR SINGLE-NUCLEOTIDE VARIANTS, MULTI-NUCLEOTIDE VARIANTS, INSERTIONS AND DELETIONS FROM DNA, FUSIONS IN 24 GENES AND SPLICE VARIANTS IN 1 GENE FROM RNA, AND TUMOR MUTATION BURDEN
Source: CMS coverage guidance
CPT 0329Uhigh
ONCOLOGY (NEOPLASIA), EXOME AND TRANSCRIPTOME SEQUENCE ANALYSIS FOR SEQUENCE VARIANTS, GENE COPY NUMBER AMPLIFICATIONS AND DELETIONS, GENE REARRANGEMENTS, MICROSATELLITE INSTABILITY AND TUMOR MUTATIONAL BURDEN UTILIZING DNA AND RNA FROM TUMOR WITH DNA FROM NORMAL BLOOD OR SALIVA FOR SUBTRACTION, REPORT OF CLINICALLY SIGNIFICANT MUTATION(S) WITH THERAPY ASSOCIATIONS
Source: CMS coverage guidance
CPT 0340Uhigh
ONCOLOGY (PAN-CANCER), ANALYSIS OF MINIMAL RESIDUAL DISEASE (MRD) FROM PLASMA, WITH ASSAYS PERSONALIZED TO EACH PATIENT BASED ON PRIOR NEXT-GENERATION SEQUENCING OF THE PATIENT'S TUMOR AND GERMLINE DNA, REPORTED AS ABSENCE OR PRESENCE OF MRD, WITH DISEASE-BURDEN CORRELATION, IF APPROPRIATE
Source: CMS coverage guidance
CPT 0422Uhigh
ONCOLOGY (PAN-SOLID TUMOR), ANALYSIS OF DNA BIOMARKER RESPONSE TO ANTI-CANCER THERAPY USING CELL-FREE CIRCULATING DNA, BIOMARKER COMPARISON TO A PREVIOUS BASELINE PRE-TREATMENT CELL-FREE CIRCULATING DNA ANALYSIS USING NEXT-GENERATION SEQUENCING, ALGORITHM REPORTED AS A QUANTITATIVE CHANGE FROM BASELINE, INCLUDING SPECIFIC ALTERATIONS, IF APPROPRIATE
Source: CMS coverage guidance
Coding guidelines
Common synonyms
Merkel cell carcinoma, unspecifiedMerkel cell carcinoma
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.