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ICD10BillableValid for clinical use

ICD-10 Code C61: Malignant neoplasm of prostate

C61 is a billable ICD-10 diagnosis code used to classify Malignant neoplasm of prostate in medical records and claims. You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records. ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).

What is this code?

ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).

When is it used?

  • May be used when a clinician documents malignant neoplasm of prostate in a patient's medical record.
  • May appear in hospital records, claims, referrals, and clinical documentation.
  • This code can be used as a clinically usable diagnosis entry in standardized coding workflows.

What it does not mean

  • A code alone does not explain severity, treatment plan, or outcome.
  • A medical code should not be treated as a substitute for a doctor's diagnosis or advice.

Code hierarchy

chapter
2Neoplasms (C00-D49)
block
C00-C96Malignant neoplasms
block
C00-C75Malignant neoplasms, stated or presumed to be primary (of specified sites), and certain specified histologies, except neuroendocrine, and of lymphoid, hematopoietic and related tissue
block
C60-C63Malignant neoplasms of male genital organs
currentC60-C63

Official coding notes

Applicable to
  • code, if applicable, to identify:
  • hormone sensitivity status (Z19.1-Z19.2)
  • rising PSA following treatment for malignant neoplasm of prostate (R97.21)
Excludes1 (do not code together)
  • malignant neoplasm of seminal vesicle (C63.7)
Use additional code
  • code, if applicable, to identify:
  • hormone sensitivity status (Z19.1-Z19.2)
  • rising PSA following treatment for malignant neoplasm of prostate (R97.21)

Where you may see this code

You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.

Related specialists

OncologistGeneral Physician

Coverage-related procedures and services

CPT 81479high
UNLISTED MOLECULAR PATHOLOGY PROCEDURE
Source: CMS coverage guidance
CPT 81445high
SOLID ORGAN NEOPLASM, GENOMIC SEQUENCE ANALYSIS PANEL, 5-50 GENES, INTERROGATION FOR SEQUENCE VARIANTS AND COPY NUMBER VARIANTS OR REARRANGEMENTS, IF PERFORMED; DNA ANALYSIS OR COMBINED DNA AND RNA ANALYSIS
Source: CMS coverage guidance
CPT 81542high
ONCOLOGY (PROSTATE), MRNA, MICROARRAY GENE EXPRESSION PROFILING OF 22 CONTENT GENES, UTILIZING FORMALIN-FIXED PARAFFIN-EMBEDDED TISSUE, ALGORITHM REPORTED AS METASTASIS RISK SCORE
Source: CMS coverage guidance
CPT 81215high
BRCA1 (BRCA1, DNA REPAIR ASSOCIATED) (EG, HEREDITARY BREAST AND OVARIAN CANCER) GENE ANALYSIS; KNOWN FAMILIAL VARIANT
Source: CMS coverage guidance
CPT 81162high
BRCA1 (BRCA1, DNA REPAIR ASSOCIATED), BRCA2 (BRCA2, DNA REPAIR ASSOCIATED) (EG, HEREDITARY BREAST AND OVARIAN CANCER) GENE ANALYSIS; FULL SEQUENCE ANALYSIS AND FULL DUPLICATION/DELETION ANALYSIS (IE, DETECTION OF LARGE GENE REARRANGEMENTS)
Source: CMS coverage guidance
CPT 81217high
BRCA2 (BRCA2, DNA REPAIR ASSOCIATED) (EG, HEREDITARY BREAST AND OVARIAN CANCER) GENE ANALYSIS; KNOWN FAMILIAL VARIANT
Source: CMS coverage guidance

Coding guidelines

Compatibility

Legacy and official ICD code match exactly.
Legacy codes
C61

Common synonyms

Malignant neoplasm of prostate

Frequently asked questions

Code details

CodeC61
SystemICD10
Display nameMalignant neoplasm of prostate
ChapterNeoplasms (C00-D49)
BlockMalignant neoplasms of male genital organs

Flags

BillableYes
Valid clinical useYes

Source

SourceICD-10
Version2026-annual
Releaseannual
Year2026

Index terms

Matched terms
AdenocarcinomaCarcinoma(malignant)Cystadenocarcinoma

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.