ICD10BillableValid for clinical use
ICD-10 Code C78.6: Secondary malignant neoplasm of retroperitoneum and peritoneum
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).
When is it used?
- May be used when a clinician documents secondary malignant neoplasm of retroperitoneum and peritoneum in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code can be used as a clinically usable diagnosis entry in standardized coding workflows.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
Code hierarchy
chapter
2Neoplasms (C00-D49)
block
C00-C96Malignant neoplasms
block
C76-C80Malignant neoplasms of ill-defined, other secondary and unspecified sites
category
C78Secondary malignant neoplasm of respiratory and digestive organs
currentC78
Where you may see this code
You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.
Related specialists
OncologistGeneral Physician
Related codes
C78.0Secondary malignant neoplasm of lungcategoryC78.1Secondary malignant neoplasm of mediastinumcodeC78.2Secondary malignant neoplasm of pleuracodeC78.3Secondary malignant neoplasm of other and unspecified respiratory organscategoryC78.4Secondary malignant neoplasm of small intestinecodeC78.5Secondary malignant neoplasm of large intestine and rectumcodeC78.7Secondary malignant neoplasm of liver and intrahepatic bile ductcodeC78.8Secondary malignant neoplasm of other and unspecified digestive organscategory
Sibling codes
C78.0Secondary malignant neoplasm of lungC78.1Secondary malignant neoplasm of mediastinumbillableC78.2Secondary malignant neoplasm of pleurabillableC78.3Secondary malignant neoplasm of other and unspecified respiratory organsC78.4Secondary malignant neoplasm of small intestinebillableC78.5Secondary malignant neoplasm of large intestine and rectumbillableC78.7Secondary malignant neoplasm of liver and intrahepatic bile ductbillableC78.8Secondary malignant neoplasm of other and unspecified digestive organs
Coverage-related procedures and services
CPT 81479high
UNLISTED MOLECULAR PATHOLOGY PROCEDURE
Source: CMS coverage guidance
CPT 81276high
KRAS (KIRSTEN RAT SARCOMA VIRAL ONCOGENE HOMOLOG) (EG, CARCINOMA) GENE ANALYSIS; ADDITIONAL VARIANT(S) (EG, CODON 61, CODON 146)
Source: CMS coverage guidance
CPT 81275high
KRAS (KIRSTEN RAT SARCOMA VIRAL ONCOGENE HOMOLOG) (EG, CARCINOMA) GENE ANALYSIS; VARIANTS IN EXON 2 (EG, CODONS 12 AND 13)
Source: CMS coverage guidance
CPT 81311high
NRAS (NEUROBLASTOMA RAS VIRAL [V-RAS] ONCOGENE HOMOLOG) (EG, COLORECTAL CARCINOMA), GENE ANALYSIS, VARIANTS IN EXON 2 (EG, CODONS 12 AND 13) AND EXON 3 (EG, CODON 61)
Source: CMS coverage guidance
CPT 81540high
ONCOLOGY (TUMOR OF UNKNOWN ORIGIN), MRNA, GENE EXPRESSION PROFILING BY REAL-TIME RT-PCR OF 92 GENES (87 CONTENT AND 5 HOUSEKEEPING) TO CLASSIFY TUMOR INTO MAIN CANCER TYPE AND SUBTYPE, UTILIZING FORMALIN-FIXED PARAFFIN-EMBEDDED TISSUE, ALGORITHM REPORTED AS A PROBABILITY OF A PREDICTED MAIN CANCER TYPE AND SUBTYPE
Source: CMS coverage guidance
CPT 88182high
FLOW CYTOMETRY, CELL CYCLE OR DNA ANALYSIS
Source: CMS coverage guidance
Mapped diagnoses and classifications
SNOMED_CT 255121007high
Carcinomatosis of peritoneal cavity
Source: SNOMED International ICD-10 map
SNOMED_CT 836274002high
Carcinomatosis of peritoneum
Source: SNOMED International ICD-10 map
SNOMED_CT 236005001high
Malignant ascites
Source: SNOMED International ICD-10 map
SNOMED_CT 1268354009high
Metastatic clear cell adenocarcinoma to peritoneum
Source: SNOMED International ICD-10 map
SNOMED_CT 94626004high
Metastatic malignant neoplasm to omentum
Source: SNOMED International ICD-10 map
SNOMED_CT 94472007high
Metastatic malignant neoplasm to parietal peritoneum
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy and official ICD code match exactly.
Legacy codes
C78.6
Common synonyms
Secondary malignant neoplasm of retroperitoneum and peritoneum
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.