What does ICD-10 code C80 mean?

ICD-10 code C80 is the standardized code used for malignant neoplasm without specification of site in medical records and coding systems.

When is ICD-10 code C80 used?

Doctors, hospitals, and insurers may use ICD-10 code C80 when recording malignant neoplasm without specification of site in a standardized format. This entry may also act as a broader category that points toward more specific child codes.

Does ICD-10 code C80 confirm a diagnosis?

No. A code helps standardize documentation and claims, but it should not be read as a substitute for a clinician's full assessment.

ICD10

ICD-10 Code C80: Malignant neoplasm without specification of site

Name: ICD-10 Code C80: Malignant neoplasm without specification of site
Creator: HealthAssure Clinical Team
Published: 2026-05-21T06:02:47.297Z

C80 is an ICD-10 diagnosis entry used to group records related to Malignant neoplasm without specification of site. You may see this entry in coding references, medical records, or claims workflows when a broader diagnosis category is being reviewed before a more specific code is chosen. ICD-10 entries help standardize how diagnoses are organized for coding, reporting, analytics, and documentation. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

ICD-10 entries help standardize how diagnoses are organized for coding, reporting, analytics, and documentation. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).

When is it used?

May be used when a clinician documents malignant neoplasm without specification of site in a patient's medical record.
May appear in hospital records, claims, referrals, and clinical documentation.
This code may act more like a grouping or parent code, so a more specific child code may be used in final documentation when available.

What it does not mean

A code alone does not explain severity, treatment plan, or outcome.
A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
This entry may represent a broader category rather than the most specific billable code.

Code hierarchy

chapter

2Neoplasms (C00-D49)

block

C00-C96Malignant neoplasms

block

C76-C80Malignant neoplasms of ill-defined, other secondary and unspecified sites

currentC76-C80

Official coding notes

Excludes1 (do not code together)

malignant carcinoid tumor of unspecified site (C7A.00)
malignant neoplasm of specified multiple sites- code to each site

Where you may see this code

You may see this entry in coding references, medical records, or claims workflows when a broader diagnosis category is being reviewed before a more specific code is chosen.

Related specialists

OncologistGeneral Physician

Sibling codes

C7AMalignant neuroendocrine tumors (C7A)C7BSecondary neuroendocrine tumors (C7B)

Coding guidelines

Compatibility

Legacy code aligns to an official FY 2026 category. Frontend should resolve to the official category page and surface the billable child codes.

Legacy codes

C80

Replacement codes

C80.0 — Disseminated malignant neoplasm, unspecifiedC80.1 — Malignant (primary) neoplasm, unspecifiedC80.2 — Malignant neoplasm associated with transplanted organ

Common synonyms

Malignant neoplasm without specification of site

Frequently asked questions

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.