ICD10
ICD-10 Code C88.2: Heavy chain disease
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 entries help standardize how diagnoses are organized for coding, reporting, analytics, and documentation. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).
When is it used?
- May be used when a clinician documents heavy chain disease in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code may act more like a grouping or parent code, so a more specific child code may be used in final documentation when available.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
- This entry may represent a broader category rather than the most specific billable code.
Code hierarchy
chapter
2Neoplasms (C00-D49)
block
C00-C96Malignant neoplasms
block
C81-C96Malignant neoplasms of lymphoid, hematopoietic and related tissue
category
C88Malignant immunoproliferative diseases and certain other B-cell lymphomas
currentC88
Official coding notes
Inclusion terms
- Franklin disease
- Gamma heavy chain disease
- Mu heavy chain disease
Where you may see this code
You may see this entry in coding references, medical records, or claims workflows when a broader diagnosis category is being reviewed before a more specific code is chosen.
Related specialists
OncologistGeneral Physician
Related codes
Sibling codes
Mapped diagnoses and classifications
SNOMED_CT 109982002high
Alpha heavy chain disease (clinical)
Source: SNOMED International ICD-10 map
SNOMED_CT 123313007high
Alpha heavy chain disease, enteric form
Source: SNOMED International ICD-10 map
SNOMED_CT 109984001high
Gamma heavy chain disease (clinical)
Source: SNOMED International ICD-10 map
SNOMED_CT 68979007high
Heavy chain disease
Source: SNOMED International ICD-10 map
SNOMED_CT 61493004high
Mu heavy chain disease
Source: SNOMED International ICD-10 map
SNOMED_CT 1148888004high
Nodular glomerulosclerosis due to heavy chain deposition disease
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy code aligns to an official FY 2026 category. Frontend should resolve to the official category page and surface the billable child codes.
Legacy codes
C88.2
Replacement codes
C88.20 — Heavy chain disease not having achieved remissionC88.21 — Heavy chain disease, in remission
Common synonyms
Heavy chain disease
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.