ICD10
ICD-10 Code C91.4: Hairy cell leukemia
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 entries help standardize how diagnoses are organized for coding, reporting, analytics, and documentation. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).
When is it used?
- May be used when a clinician documents hairy cell leukemia in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code may act more like a grouping or parent code, so a more specific child code may be used in final documentation when available.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
- This entry may represent a broader category rather than the most specific billable code.
Code hierarchy
chapter
2Neoplasms (C00-D49)
block
C00-C96Malignant neoplasms
block
C81-C96Malignant neoplasms of lymphoid, hematopoietic and related tissue
category
C91Lymphoid leukemia
currentC91
Official coding notes
Inclusion terms
- Leukemic reticuloendotheliosis
Where you may see this code
You may see this entry in coding references, medical records, or claims workflows when a broader diagnosis category is being reviewed before a more specific code is chosen.
Related specialists
OncologistGeneral Physician
Related codes
Sibling codes
C91.0Acute lymphoblastic leukemia [ALL]C91.1Chronic lymphocytic leukemia of B-cell typeC91.3Prolymphocytic leukemia of B-cell typeC91.5Adult T-cell lymphoma/leukemia (HTLV-1-associated)C91.6Prolymphocytic leukemia of T-cell typeC91.AMature B-cell leukemia Burkitt-typeC91.ZOther lymphoid leukemiaC91.9Lymphoid leukemia, unspecified
Mapped diagnoses and classifications
SNOMED_CT 307341004high
Atypical hairy cell leukemia
Source: SNOMED International ICD-10 map
SNOMED_CT 277568007high
Hairy cell leukaemia variant
Source: SNOMED International ICD-10 map
SNOMED_CT 118613001high
Hairy cell leukemia (clinical)
Source: SNOMED International ICD-10 map
SNOMED_CT 93151007high
Hairy cell leukemia of spleen
Source: SNOMED International ICD-10 map
SNOMED_CT 404139001high
Leukaemic infiltration of skin in hairy-cell leukaemia
Source: SNOMED International ICD-10 map
SNOMED_CT 188645002high
Leukaemic reticuloendotheliosis of lymph nodes of head, face and neck
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy code aligns to an official FY 2026 category. Frontend should resolve to the official category page and surface the billable child codes.
Legacy codes
C91.4
Replacement codes
C91.40 — Hairy cell leukemia not having achieved remissionC91.41 — Hairy cell leukemia, in remissionC91.42 — Hairy cell leukemia, in relapse
Common synonyms
Hairy cell leukemia
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.