ICD10BillableValid for clinical use
ICD-10 Code D21.0: Benign neoplasm of connective and other soft tissue of head, face and neck
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).
When is it used?
- May be used when a clinician documents benign neoplasm of connective and other soft tissue of head, face and neck in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code can be used as a clinically usable diagnosis entry in standardized coding workflows.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
Code hierarchy
chapter
2Neoplasms (C00-D49)
block
D10-D36Benign neoplasms, except benign neuroendocrine tumors
category
D21Other benign neoplasms of connective and other soft tissue
currentD21
Official coding notes
Inclusion terms
- Benign neoplasm of connective tissue of ear
- Benign neoplasm of connective tissue of eyelid
Excludes1 (do not code together)
- benign neoplasm of connective tissue of orbit (D31.6-)
Where you may see this code
You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.
Related specialists
OncologistGeneral Physician
Related codes
D21.1Benign neoplasm of connective and other soft tissue of upper limb, including shouldercategoryD21.2Benign neoplasm of connective and other soft tissue of lower limb, including hipcategoryD21.3Benign neoplasm of connective and other soft tissue of thoraxcodeD21.4Benign neoplasm of connective and other soft tissue of abdomencodeD21.5Benign neoplasm of connective and other soft tissue of pelviscodeD21.6Benign neoplasm of connective and other soft tissue of trunk, unspecifiedcodeD21.9Benign neoplasm of connective and other soft tissue, unspecifiedcode
Sibling codes
D21.1Benign neoplasm of connective and other soft tissue of upper limb, including shoulderD21.2Benign neoplasm of connective and other soft tissue of lower limb, including hipD21.3Benign neoplasm of connective and other soft tissue of thoraxbillableD21.4Benign neoplasm of connective and other soft tissue of abdomenbillableD21.5Benign neoplasm of connective and other soft tissue of pelvisbillableD21.6Benign neoplasm of connective and other soft tissue of trunk, unspecifiedbillableD21.9Benign neoplasm of connective and other soft tissue, unspecifiedbillable
Coverage-related procedures and services
CPT 70460high
COMPUTED TOMOGRAPHY, HEAD OR BRAIN; WITH CONTRAST MATERIAL(S)
Source: CMS coverage guidance
CPT 70450high
COMPUTED TOMOGRAPHY, HEAD OR BRAIN; WITHOUT CONTRAST MATERIAL
Source: CMS coverage guidance
CPT 70470high
COMPUTED TOMOGRAPHY, HEAD OR BRAIN; WITHOUT CONTRAST MATERIAL, FOLLOWED BY CONTRAST MATERIAL(S) AND FURTHER SECTIONS
Source: CMS coverage guidance
CPT 95940high
CONTINUOUS INTRAOPERATIVE NEUROPHYSIOLOGY MONITORING IN THE OPERATING ROOM, ONE ON ONE MONITORING REQUIRING PERSONAL ATTENDANCE, EACH 15 MINUTES (LIST SEPARATELY IN ADDITION TO CODE FOR PRIMARY PROCEDURE)
Source: CMS coverage guidance
HCPCS G0453high
CONTINUOUS INTRAOPERATIVE NEUROPHYSIOLOGY MONITORING, FROM OUTSIDE THE OPERATING ROOM (REMOTE OR NEARBY), PER PATIENT, (ATTENTION DIRECTED EXCLUSIVELY TO ONE PATIENT) EACH 15 MINUTES (LIST IN ADDITION TO PRIMARY PROCEDURE)
Source: CMS coverage guidance
CPT 11440high
EXCISION, OTHER BENIGN LESION INCLUDING MARGINS, EXCEPT SKIN TAG (UNLESS LISTED ELSEWHERE), FACE, EARS, EYELIDS, NOSE, LIPS, MUCOUS MEMBRANE; EXCISED DIAMETER 0.5 CM OR LESS
Source: CMS coverage guidance
Mapped diagnoses and classifications
SNOMED_CT 91997004high
Benign neoplasm of blood vessel of face
Source: SNOMED International ICD-10 map
SNOMED_CT 92002004high
Benign neoplasm of blood vessel of head
Source: SNOMED International ICD-10 map
SNOMED_CT 92007005high
Benign neoplasm of blood vessel of neck
Source: SNOMED International ICD-10 map
SNOMED_CT 447798009high
Benign neoplasm of connective tissue of head and/or neck
Source: SNOMED International ICD-10 map
SNOMED_CT 92225009high
Benign neoplasm of muscle of face
Source: SNOMED International ICD-10 map
SNOMED_CT 92226005high
Benign neoplasm of muscle of head
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy and official ICD code match exactly.
Legacy codes
D21.0
Common synonyms
Benign neoplasm of connective and other soft tissue of head, face and neck
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.