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ICD10BillableValid for clinical use

ICD-10 Code D40.0: Neoplasm of uncertain behavior of prostate

D40.0 is a billable ICD-10 diagnosis code used to classify Neoplasm of uncertain behavior of prostate in medical records and claims. You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records. ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).

What is this code?

ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).

When is it used?

  • May be used when a clinician documents neoplasm of uncertain behavior of prostate in a patient's medical record.
  • May appear in hospital records, claims, referrals, and clinical documentation.
  • This code can be used as a clinically usable diagnosis entry in standardized coding workflows.

What it does not mean

  • A code alone does not explain severity, treatment plan, or outcome.
  • A medical code should not be treated as a substitute for a doctor's diagnosis or advice.

Code hierarchy

chapter
2Neoplasms (C00-D49)
block
D37-D48Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
category
D40Neoplasm of uncertain behavior of male genital organs
currentD40

Where you may see this code

You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.

Related specialists

OncologistGeneral Physician

Coverage-related procedures and services

CPT 0403Uhigh
ONCOLOGY (PROSTATE), MRNA, GENE EXPRESSION PROFILING OF 18 GENES, FIRST-CATCH URINE, ALGORITHM REPORTED AS PERCENTAGE OF LIKELIHOOD OF DETECTING CLINICALLY SIGNIFICANT PROSTATE CANCER
Source: CMS coverage guidance
CPT 0339Uhigh
ONCOLOGY (PROSTATE), MRNA EXPRESSION PROFILING OF HOXC6 AND DLX1, REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION (RT-PCR), FIRST-VOID URINE FOLLOWING DIGITAL RECTAL EXAMINATION, ALGORITHM REPORTED AS PROBABILITY OF HIGH-GRADE CANCER
Source: CMS coverage guidance
CPT 81551high
ONCOLOGY (PROSTATE), PROMOTER METHYLATION PROFILING BY REAL-TIME PCR OF 3 GENES (GSTP1, APC, RASSF1), UTILIZING FORMALIN-FIXED PARAFFIN-EMBEDDED TISSUE, ALGORITHM REPORTED AS A LIKELIHOOD OF PROSTATE CANCER DETECTION ON REPEAT BIOPSY
Source: CMS coverage guidance
CPT 81313high
PCA3/KLK3 (PROSTATE CANCER ANTIGEN 3 [NON-PROTEIN CODING]/KALLIKREIN-RELATED PEPTIDASE 3 [PROSTATE SPECIFIC ANTIGEN]) RATIO (EG, PROSTATE CANCER)
Source: CMS coverage guidance
CPT 81479high
UNLISTED MOLECULAR PATHOLOGY PROCEDURE
Source: CMS coverage guidance
CPT 88182high
FLOW CYTOMETRY, CELL CYCLE OR DNA ANALYSIS
Source: CMS coverage guidance

Coding guidelines

Compatibility

Legacy and official ICD code match exactly.
Legacy codes
D40.0

Common synonyms

Neoplasm of uncertain behavior of prostate

Frequently asked questions

Code details

CodeD40.0
SystemICD10
Display nameNeoplasm of uncertain behavior of prostate
ChapterNeoplasms (C00-D49)
BlockNeoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes

Flags

BillableYes
Valid clinical useYes

Source

SourceICD-10
Version2026-annual
Releaseannual
Year2026

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.