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ICD10BillableValid for clinical use

ICD-10 Code D46.B: Refractory cytopenia with multilineage dysplasia and ring sideroblasts

D46.B is a billable ICD-10 diagnosis code used to classify Refractory cytopenia with multilineage dysplasia and ring sideroblasts in medical records and claims. You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records. ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).

What is this code?

ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).

When is it used?

  • May be used when a clinician documents refractory cytopenia with multilineage dysplasia and ring sideroblasts in a patient's medical record.
  • May appear in hospital records, claims, referrals, and clinical documentation.
  • This code can be used as a clinically usable diagnosis entry in standardized coding workflows.

What it does not mean

  • A code alone does not explain severity, treatment plan, or outcome.
  • A medical code should not be treated as a substitute for a doctor's diagnosis or advice.

Code hierarchy

chapter
2Neoplasms (C00-D49)
block
D37-D48Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
category
D46Myelodysplastic syndromes
currentD46

Official coding notes

Inclusion terms
  • RCMD RS

Where you may see this code

You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.

Related specialists

OncologistGeneral Physician

Coverage-related procedures and services

CPT 81479high
UNLISTED MOLECULAR PATHOLOGY PROCEDURE
Source: CMS coverage guidance
CPT 81450high
HEMATOLYMPHOID NEOPLASM OR DISORDER, GENOMIC SEQUENCE ANALYSIS PANEL, 5-50 GENES, INTERROGATION FOR SEQUENCE VARIANTS, AND COPY NUMBER VARIANTS OR REARRANGEMENTS, OR ISOFORM EXPRESSION OR MRNA EXPRESSION LEVELS, IF PERFORMED; DNA ANALYSIS OR COMBINED DNA AND RNA ANALYSIS
Source: CMS coverage guidance
CPT 88291high
CYTOGENETICS AND MOLECULAR CYTOGENETICS, INTERPRETATION AND REPORT
Source: CMS coverage guidance
CPT 81451high
HEMATOLYMPHOID NEOPLASM OR DISORDER, GENOMIC SEQUENCE ANALYSIS PANEL, 5-50 GENES, INTERROGATION FOR SEQUENCE VARIANTS, AND COPY NUMBER VARIANTS OR REARRANGEMENTS, OR ISOFORM EXPRESSION OR MRNA EXPRESSION LEVELS, IF PERFORMED; RNA ANALYSIS
Source: CMS coverage guidance
CPT 88273high
MOLECULAR CYTOGENETICS; CHROMOSOMAL IN SITU HYBRIDIZATION, ANALYZE 10-30 CELLS (EG, FOR MICRODELETIONS)
Source: CMS coverage guidance
CPT 88271high
MOLECULAR CYTOGENETICS; DNA PROBE, EACH (EG, FISH)
Source: CMS coverage guidance

Coding guidelines

Common synonyms

Refractory cytopenia with multilineage dysplasia and ring sideroblasts

Frequently asked questions

Code details

CodeD46.B
SystemICD10
Display nameRefractory cytopenia with multilineage dysplasia and ring sideroblasts
ChapterNeoplasms (C00-D49)
BlockNeoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes

Flags

BillableYes
Valid clinical useYes

Source

SourceICD-10
Version2026-annual
Releaseannual
Year2026

Index terms

Matched terms
CytopeniaSyndrome

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.