ICD10BillableValid for clinical use
ICD-10 Code D47.4: Osteomyelofibrosis
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).
When is it used?
- May be used when a clinician documents osteomyelofibrosis in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code can be used as a clinically usable diagnosis entry in standardized coding workflows.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
Code hierarchy
chapter
2Neoplasms (C00-D49)
block
D37-D48Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
category
D47Other neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue
currentD47
Official coding notes
Inclusion terms
- Chronic idiopathic myelofibrosis
- Myelofibrosis (idiopathic) (with myeloid metaplasia)
- Myelosclerosis (megakaryocytic) with myeloid metaplasia
- Secondary myelofibrosis in myeloproliferative disease
Excludes1 (do not code together)
- acute myelofibrosis (C94.4-)
Where you may see this code
You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.
Related specialists
OncologistGeneral Physician
Related codes
D47.0Mast cell neoplasms of uncertain behaviorcategoryD47.1Chronic myeloproliferative diseasecodeD47.2Monoclonal gammopathycodeD47.3Essential (hemorrhagic) thrombocythemiacodeD47.ZOther specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissuecategoryD47.9Neoplasm of uncertain behavior of lymphoid, hematopoietic and related tissue, unspecifiedcode
Sibling codes
D47.0Mast cell neoplasms of uncertain behaviorD47.1Chronic myeloproliferative diseasebillableD47.2Monoclonal gammopathybillableD47.3Essential (hemorrhagic) thrombocythemiabillableD47.ZOther specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissueD47.9Neoplasm of uncertain behavior of lymphoid, hematopoietic and related tissue, unspecifiedbillable
Coverage-related procedures and services
CPT 81479high
UNLISTED MOLECULAR PATHOLOGY PROCEDURE
Source: CMS coverage guidance
CPT 81450high
HEMATOLYMPHOID NEOPLASM OR DISORDER, GENOMIC SEQUENCE ANALYSIS PANEL, 5-50 GENES, INTERROGATION FOR SEQUENCE VARIANTS, AND COPY NUMBER VARIANTS OR REARRANGEMENTS, OR ISOFORM EXPRESSION OR MRNA EXPRESSION LEVELS, IF PERFORMED; DNA ANALYSIS OR COMBINED DNA AND RNA ANALYSIS
Source: CMS coverage guidance
CPT 0040Uhigh
BCR/ABL1 (T(9;22)) (EG, CHRONIC MYELOGENOUS LEUKEMIA) TRANSLOCATION ANALYSIS, MAJOR BREAKPOINT, QUANTITATIVE
Source: CMS coverage guidance
CPT 81206high
BCR/ABL1 (T(9;22)) (EG, CHRONIC MYELOGENOUS LEUKEMIA) TRANSLOCATION ANALYSIS; MAJOR BREAKPOINT, QUALITATIVE OR QUANTITATIVE
Source: CMS coverage guidance
CPT 81207high
BCR/ABL1 (T(9;22)) (EG, CHRONIC MYELOGENOUS LEUKEMIA) TRANSLOCATION ANALYSIS; MINOR BREAKPOINT, QUALITATIVE OR QUANTITATIVE
Source: CMS coverage guidance
CPT 81208high
BCR/ABL1 (T(9;22)) (EG, CHRONIC MYELOGENOUS LEUKEMIA) TRANSLOCATION ANALYSIS; OTHER BREAKPOINT, QUALITATIVE OR QUANTITATIVE
Source: CMS coverage guidance
Mapped diagnoses and classifications
SNOMED_CT 1259049004high
Castleman disease with immunoglobulin M monoclonal gammopathy of uncertain significance
Source: SNOMED International ICD-10 map
SNOMED_CT 699293000high
Ischemic myelofibrosis
Source: SNOMED International ICD-10 map
SNOMED_CT 1156784009high
Localized Castleman disease
Source: SNOMED International ICD-10 map
SNOMED_CT 1156805003high
Multicentric Castleman disease
Source: SNOMED International ICD-10 map
SNOMED_CT 1153374001high
Myelofibrosis caused by drug
Source: SNOMED International ICD-10 map
SNOMED_CT 871541008high
Post-essential thrombocythaemia myelofibrosis
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy and official ICD code match exactly.
Legacy codes
D47.4
Common synonyms
Osteomyelofibrosis
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.