ICD10BillableValid for clinical use
ICD-10 Code D48.3: Neoplasm of uncertain behavior of retroperitoneum
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Neoplasms (C00-D49).
When is it used?
- May be used when a clinician documents neoplasm of uncertain behavior of retroperitoneum in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code can be used as a clinically usable diagnosis entry in standardized coding workflows.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
Code hierarchy
chapter
2Neoplasms (C00-D49)
block
D37-D48Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
category
D48Neoplasm of uncertain behavior of other and unspecified sites
currentD48
Where you may see this code
You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.
Related specialists
OncologistGeneral Physician
Related codes
D48.0Neoplasm of uncertain behavior of bone and articular cartilagecodeD48.1Neoplasm of uncertain behavior of connective and other soft tissuecategoryD48.2Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous systemcodeD48.4Neoplasm of uncertain behavior of peritoneumcodeD48.5Neoplasm of uncertain behavior of skincodeD48.6Neoplasm of uncertain behavior of breastcategoryD48.7Neoplasm of uncertain behavior of other specified sitescodeD48.9Neoplasm of uncertain behavior, unspecifiedcode
Sibling codes
D48.0Neoplasm of uncertain behavior of bone and articular cartilagebillableD48.1Neoplasm of uncertain behavior of connective and other soft tissueD48.2Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous systembillableD48.4Neoplasm of uncertain behavior of peritoneumbillableD48.5Neoplasm of uncertain behavior of skinbillableD48.6Neoplasm of uncertain behavior of breastD48.7Neoplasm of uncertain behavior of other specified sitesbillableD48.9Neoplasm of uncertain behavior, unspecifiedbillable
Coverage-related procedures and services
CPT 81540high
ONCOLOGY (TUMOR OF UNKNOWN ORIGIN), MRNA, GENE EXPRESSION PROFILING BY REAL-TIME RT-PCR OF 92 GENES (87 CONTENT AND 5 HOUSEKEEPING) TO CLASSIFY TUMOR INTO MAIN CANCER TYPE AND SUBTYPE, UTILIZING FORMALIN-FIXED PARAFFIN-EMBEDDED TISSUE, ALGORITHM REPORTED AS A PROBABILITY OF A PREDICTED MAIN CANCER TYPE AND SUBTYPE
Source: CMS coverage guidance
CPT 88182high
FLOW CYTOMETRY, CELL CYCLE OR DNA ANALYSIS
Source: CMS coverage guidance
CPT 88185high
FLOW CYTOMETRY, CELL SURFACE, CYTOPLASMIC, OR NUCLEAR MARKER, TECHNICAL COMPONENT ONLY; EACH ADDITIONAL MARKER (LIST SEPARATELY IN ADDITION TO CODE FOR FIRST MARKER)
Source: CMS coverage guidance
CPT 88184high
FLOW CYTOMETRY, CELL SURFACE, CYTOPLASMIC, OR NUCLEAR MARKER, TECHNICAL COMPONENT ONLY; FIRST MARKER
Source: CMS coverage guidance
CPT 88189high
FLOW CYTOMETRY, INTERPRETATION; 16 OR MORE MARKERS
Source: CMS coverage guidance
CPT 88187high
FLOW CYTOMETRY, INTERPRETATION; 2 TO 8 MARKERS
Source: CMS coverage guidance
Mapped diagnoses and classifications
SNOMED_CT 425607009high
Haemangioendothelioma of retroperitoneum
Source: SNOMED International ICD-10 map
SNOMED_CT 126873003high
Neoplasm of periadrenal tissue
Source: SNOMED International ICD-10 map
SNOMED_CT 126874009high
Neoplasm of perirenal tissue
Source: SNOMED International ICD-10 map
SNOMED_CT 236019001high
Neoplasm of peritoneum and retroperitoneum
Source: SNOMED International ICD-10 map
SNOMED_CT 126875005high
Neoplasm of retrocecal tissue
Source: SNOMED International ICD-10 map
SNOMED_CT 126872008high
Neoplasm of retroperitoneum
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy and official ICD code match exactly.
Legacy codes
D48.3
Common synonyms
Neoplasm of uncertain behavior of retroperitoneum
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.