ICD10

ICD-10 Code D57: Sickle-cell disorders

D57 is an ICD-10 diagnosis entry used to group records related to Sickle-cell disorders. You may see this entry in coding references, medical records, or claims workflows when a broader diagnosis category is being reviewed before a more specific code is chosen. ICD-10 entries help standardize how diagnoses are organized for coding, reporting, analytics, and documentation. This code sits within the broader ICD-10 area for Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89).

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

ICD-10 entries help standardize how diagnoses are organized for coding, reporting, analytics, and documentation. This code sits within the broader ICD-10 area for Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89).

When is it used?

  • May be used when a clinician documents sickle-cell disorders in a patient's medical record.
  • May appear in hospital records, claims, referrals, and clinical documentation.
  • This code may act more like a grouping or parent code, so a more specific child code may be used in final documentation when available.

What it does not mean

  • A code alone does not explain severity, treatment plan, or outcome.
  • A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
  • This entry may represent a broader category rather than the most specific billable code.

Code hierarchy

chapter
3Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
block
D55-D59Hemolytic anemias
currentD55-D59

Official coding notes

Applicable to
  • code for any associated fever (R50.81)
Excludes1 (do not code together)
  • other hemoglobinopathies (D58.-)
Use additional code
  • code for any associated fever (R50.81)

Where you may see this code

You may see this entry in coding references, medical records, or claims workflows when a broader diagnosis category is being reviewed before a more specific code is chosen.

Related specialists

HematologistGeneral Physician

Coding guidelines

Compatibility

Legacy code aligns to an official FY 2026 category. Frontend should resolve to the official category page and surface the billable child codes.
Legacy codes
D57
Replacement codes
D57.1 — Sickle-cell disease without crisisD57.3 — Sickle-cell trait

Common synonyms

Sickle-cell disorders

Frequently asked questions

Code details

CodeD57
SystemICD10
Display nameSickle-cell disorders
ChapterDiseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
BlockHemolytic anemias

Flags

BillableNo
Valid clinical useNo

Source

SourceICD-10
Version2026-annual
Releaseannual
Year2026

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

ICD-10 Code D57 for Sickle-cell disorders | HealthAssure