ICD-10 Code D57.4: Sickle-cell thalassemia

What is this code?

ICD-10 entries help standardize how diagnoses are organized for coding, reporting, analytics, and documentation. This code sits within the broader ICD-10 area for Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89).

When is it used?

• May be used when a clinician documents sickle-cell thalassemia in a patient's medical record.
• May appear in hospital records, claims, referrals, and clinical documentation.
• This code may act more like a grouping or parent code, so a more specific child code may be used in final documentation when available.

What it does not mean

• A code alone does not explain severity, treatment plan, or outcome.
• A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
• This entry may represent a broader category rather than the most specific billable code.

Code hierarchy

Official coding notes

Where you may see this code

You may see this entry in coding references, medical records, or claims workflows when a broader diagnosis category is being reviewed before a more specific code is chosen.

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