ICD10BillableValid for clinical use

ICD-10 Code D68.61: Antiphospholipid syndrome

D68.61 is a billable ICD-10 diagnosis code used to classify Antiphospholipid syndrome in medical records and claims. You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records. ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89).

Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026

What is this code?

ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89).

When is it used?

  • May be used when a clinician documents antiphospholipid syndrome in a patient's medical record.
  • May appear in hospital records, claims, referrals, and clinical documentation.
  • This code can be used as a clinically usable diagnosis entry in standardized coding workflows.

What it does not mean

  • A code alone does not explain severity, treatment plan, or outcome.
  • A medical code should not be treated as a substitute for a doctor's diagnosis or advice.

Code hierarchy

chapter
3Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
block
D65-D69Coagulation defects, purpura and other hemorrhagic conditions
category
D68Other coagulation defects
category
D68.6Other thrombophilia
currentD68.6

Official coding notes

Inclusion terms
  • Anticardiolipin syndrome
  • Antiphospholipid antibody syndrome
Excludes1 (do not code together)
  • anti-phospholipid antibody, finding without diagnosis (R76.0)
Excludes2 (may code together if documented)
  • anti-phospholipid antibody with hemorrhagic disorder (D68.312)
  • lupus anticoagulant syndrome (D68.62)

Where you may see this code

You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.

Related specialists

HematologistGeneral Physician

Coverage-related procedures and services

CPT 93985high
DUPLEX SCAN OF ARTERIAL INFLOW AND VENOUS OUTFLOW FOR PREOPERATIVE VESSEL ASSESSMENT PRIOR TO CREATION OF HEMODIALYSIS ACCESS; COMPLETE BILATERAL STUDY
Source: CMS coverage guidance
CPT 93986high
DUPLEX SCAN OF ARTERIAL INFLOW AND VENOUS OUTFLOW FOR PREOPERATIVE VESSEL ASSESSMENT PRIOR TO CREATION OF HEMODIALYSIS ACCESS; COMPLETE UNILATERAL STUDY
Source: CMS coverage guidance
CPT 93970high
DUPLEX SCAN OF EXTREMITY VEINS INCLUDING RESPONSES TO COMPRESSION AND OTHER MANEUVERS; COMPLETE BILATERAL STUDY
Source: CMS coverage guidance
CPT 93971high
DUPLEX SCAN OF EXTREMITY VEINS INCLUDING RESPONSES TO COMPRESSION AND OTHER MANEUVERS; UNILATERAL OR LIMITED STUDY
Source: CMS coverage guidance
CPT 93990high
DUPLEX SCAN OF HEMODIALYSIS ACCESS (INCLUDING ARTERIAL INFLOW, BODY OF ACCESS AND VENOUS OUTFLOW)
Source: CMS coverage guidance
CPT 88182high
FLOW CYTOMETRY, CELL CYCLE OR DNA ANALYSIS
Source: CMS coverage guidance

Coding guidelines

Common synonyms

Antiphospholipid syndrome

Frequently asked questions

Code details

CodeD68.61
SystemICD10
Display nameAntiphospholipid syndrome
ChapterDiseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
BlockCoagulation defects, purpura and other hemorrhagic conditions

Flags

BillableYes
Valid clinical useYes

Source

SourceICD-10
Version2026-annual
Releaseannual
Year2026

Index terms

Matched terms
AntibodyAntibodyAntibodyAntibodyAntibodyAnticardiolipin syndromeAntiphospholipidSyndromeSyndrome

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

ICD-10 Code D68.61 for Antiphospholipid syndrome | HealthAssure