ICD10BillableValid for clinical use
ICD-10 Code E04.1: Nontoxic single thyroid nodule
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).
When is it used?
- May be used when a clinician documents nontoxic single thyroid nodule in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code can be used as a clinically usable diagnosis entry in standardized coding workflows.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
Code hierarchy
chapter
4Endocrine, nutritional and metabolic diseases (E00-E89)
block
E00-E07Disorders of thyroid gland
category
E04Other nontoxic goiter
currentE04
Official coding notes
Inclusion terms
- Colloid nodule (cystic) (thyroid)
- Nontoxic uninodular goiter
- Thyroid (cystic) nodule NOS
Where you may see this code
You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.
Related specialists
EndocrinologistGeneral Physician
Related codes
Sibling codes
Coverage-related procedures and services
CPT 81546high
ONCOLOGY (THYROID), MRNA, GENE EXPRESSION ANALYSIS OF 10,196 GENES, UTILIZING FINE NEEDLE ASPIRATE, ALGORITHM REPORTED AS A CATEGORICAL RESULT (EG, BENIGN OR SUSPICIOUS)
Source: CMS coverage guidance
CPT 81479high
UNLISTED MOLECULAR PATHOLOGY PROCEDURE
Source: CMS coverage guidance
CPT 72126high
COMPUTED TOMOGRAPHY, CERVICAL SPINE; WITH CONTRAST MATERIAL
Source: CMS coverage guidance
CPT 72125high
COMPUTED TOMOGRAPHY, CERVICAL SPINE; WITHOUT CONTRAST MATERIAL
Source: CMS coverage guidance
CPT 72127high
COMPUTED TOMOGRAPHY, CERVICAL SPINE; WITHOUT CONTRAST MATERIAL, FOLLOWED BY CONTRAST MATERIAL(S) AND FURTHER SECTIONS
Source: CMS coverage guidance
CPT 70460high
COMPUTED TOMOGRAPHY, HEAD OR BRAIN; WITH CONTRAST MATERIAL(S)
Source: CMS coverage guidance
Mapped diagnoses and classifications
SNOMED_CT 445347002high
Calcifying cyst of thyroid
Source: SNOMED International ICD-10 map
SNOMED_CT 72325004high
Cyst of thyroid
Source: SNOMED International ICD-10 map
SNOMED_CT 443821001high
Dominant nodule of thyroid
Source: SNOMED International ICD-10 map
SNOMED_CT 1137355002high
Hyperplastic thyroid nodule
Source: SNOMED International ICD-10 map
SNOMED_CT 190237002high
Non-toxic uninodular goiter
Source: SNOMED International ICD-10 map
SNOMED_CT 1388449007high
Thyroid follicular nodular disease
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy and official ICD code match exactly.
Legacy codes
E04.1
Common synonyms
Nontoxic single thyroid nodule
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.