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ICD10BillableValid for clinical use

ICD-10 Code E05.21: Thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis or storm

E05.21 is a billable ICD-10 diagnosis code used to classify Thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis or storm in medical records and claims. You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records. ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).

What is this code?

ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).

When is it used?

  • May be used when a clinician documents thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis or storm in a patient's medical record.
  • May appear in hospital records, claims, referrals, and clinical documentation.
  • This code can be used as a clinically usable diagnosis entry in standardized coding workflows.

What it does not mean

  • A code alone does not explain severity, treatment plan, or outcome.
  • A medical code should not be treated as a substitute for a doctor's diagnosis or advice.

Code hierarchy

chapter
4Endocrine, nutritional and metabolic diseases (E00-E89)
block
E00-E07Disorders of thyroid gland
category
E05Thyrotoxicosis [hyperthyroidism]
category
E05.2Thyrotoxicosis with toxic multinodular goiter
currentE05.2

Where you may see this code

You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.

Related specialists

EndocrinologistGeneral Physician

Related tests

TSH
Commonly reviewed in hyperthyroidism evaluation.
Free T4
Often reviewed alongside TSH in thyroid assessment.
Free T3
May help clarify thyroid hormone excess in hyperthyroid states.

Coding guidelines

Common synonyms

Thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis or storm

Frequently asked questions

Code details

CodeE05.21
SystemICD10
Display nameThyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis or storm
ChapterEndocrine, nutritional and metabolic diseases (E00-E89)
BlockDisorders of thyroid gland

Flags

BillableYes
Valid clinical useYes

Source

SourceICD-10
Version2026-annual
Releaseannual
Year2026

Index terms

Matched terms
Goiter(plunging) (substernal)Goiter(plunging) (substernal)Goiter(plunging) (substernal)Goiter(plunging) (substernal)Hyperthyroidism(latent) (pre-adult) (recurrent)Nodule(s), nodularNodule(s), nodularPlummer's diseaseStrumaStrumaStrumaStruma

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.