ICD10
ICD-10 Code E27.4: Other and unspecified adrenocortical insufficiency
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 entries help standardize how diagnoses are organized for coding, reporting, analytics, and documentation. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).
When is it used?
- May be used when a clinician documents other and unspecified adrenocortical insufficiency in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code may act more like a grouping or parent code, so a more specific child code may be used in final documentation when available.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
- This entry may represent a broader category rather than the most specific billable code.
Code hierarchy
chapter
4Endocrine, nutritional and metabolic diseases (E00-E89)
block
E20-E35Disorders of other endocrine glands
category
E27Other disorders of adrenal gland
currentE27
Official coding notes
Excludes1 (do not code together)
- adrenoleukodystrophy [Addison-Schilder] (E71.528)
- Waterhouse-Friderichsen syndrome (A39.1)
Where you may see this code
You may see this entry in coding references, medical records, or claims workflows when a broader diagnosis category is being reviewed before a more specific code is chosen.
Related specialists
EndocrinologistGeneral Physician
Related codes
Sibling codes
E27.0Other adrenocortical overactivitybillableE27.1Primary adrenocortical insufficiencybillableE27.2Addisonian crisisbillableE27.3Drug-induced adrenocortical insufficiencybillableE27.5Adrenomedullary hyperfunctionbillableE27.8Other specified disorders of adrenal glandbillableE27.9Disorder of adrenal gland, unspecifiedbillable
Mapped diagnoses and classifications
SNOMED_CT 237772002high
Adrenal atrophy
Source: SNOMED International ICD-10 map
SNOMED_CT 131044009high
Adrenal cortical hormone level below reference range
Source: SNOMED International ICD-10 map
SNOMED_CT 386584007high
Adrenal cortical hypofunction
Source: SNOMED International ICD-10 map
SNOMED_CT 85096001high
Adrenal infarction
Source: SNOMED International ICD-10 map
SNOMED_CT 237761007high
Adrenal insufficiency due to adrenal metastasis
Source: SNOMED International ICD-10 map
SNOMED_CT 55003009high
Adrenal medullary insufficiency
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy code aligns to an official FY 2026 category. Frontend should resolve to the official category page and surface the billable child codes.
Legacy codes
E27.4
Replacement codes
E27.40 — Unspecified adrenocortical insufficiencyE27.49 — Other adrenocortical insufficiency
Common synonyms
Other and unspecified adrenocortical insufficiencyOther and adrenocortical insufficiency
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.