HealthAssure
HealthAssureGood Life
ICD10BillableValid for clinical use

ICD-10 Code E34.321: Primary insulin-like growth factor-1 (IGF-1) deficiency

E34.321 is a billable ICD-10 diagnosis code used to classify Primary insulin-like growth factor-1 (IGF-1) deficiency in medical records and claims. You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records. ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).

Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026

What is this code?

ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).

When is it used?

  • May be used when a clinician documents primary insulin-like growth factor-1 (igf-1) deficiency in a patient's medical record.
  • May appear in hospital records, claims, referrals, and clinical documentation.
  • This code can be used as a clinically usable diagnosis entry in standardized coding workflows.

What it does not mean

  • A code alone does not explain severity, treatment plan, or outcome.
  • A medical code should not be treated as a substitute for a doctor's diagnosis or advice.

Code hierarchy

chapter
4Endocrine, nutritional and metabolic diseases (E00-E89)
block
E20-E35Disorders of other endocrine glands
category
E34Other endocrine disorders
category
E34.3Short stature due to endocrine disorder
category
E34.32Genetic causes of short stature
currentE34.32

Official coding notes

Inclusion terms
  • Acid-labile subunit gene (IGFALS) defect
  • Growth hormone gene 1 (GH1) defect with growth hormone neutralizing antibodies
  • Growth hormone insensitivity syndrome (GHIS)
  • Insulin-like growth factor 1 gene (IGF1) defect
  • Laron type short stature
  • Severe primary insulin-like growth factor-1 deficiency (SPIGFD)
  • Signal transducer and activator of transcription 5B gene (STAT5b) defect

Where you may see this code

You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.

Related specialists

EndocrinologistGeneral Physician

Coding guidelines

Common synonyms

Primary insulin-like growth factor-1 (IGF-1) deficiencyPrimary insulin-like growth factor-1Primary insulin-like growth factor-1 IGF-1 deficiency

Frequently asked questions

Code details

CodeE34.321
SystemICD10
Display namePrimary insulin-like growth factor-1 (IGF-1) deficiency
ChapterEndocrine, nutritional and metabolic diseases (E00-E89)
BlockDisorders of other endocrine glands

Flags

BillableYes
Valid clinical useYes

Source

SourceICD-10
Version2026-annual
Releaseannual
Year2026

Index terms

Matched terms
DwarfismShort, shortening, shortnessShort, shortening, shortnessShort, shortening, shortnessShort, shortening, shortnessShort, shortening, shortnessShort, shortening, shortnessShort, shortening, shortnessShort, shortening, shortness
See also
Short, stature

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

ICD-10 Code E34.321 for Primary insulin-like growth factor-1 (IGF-1) deficiency | HealthAssure