ICD10BillableValid for clinical use
ICD-10 Code E53.1: Pyridoxine deficiency
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).
When is it used?
- May be used when a clinician documents pyridoxine deficiency in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code can be used as a clinically usable diagnosis entry in standardized coding workflows.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
Code hierarchy
chapter
4Endocrine, nutritional and metabolic diseases (E00-E89)
block
E50-E64Other nutritional deficiencies
category
E53Deficiency of other B group vitamins
currentE53
Official coding notes
Inclusion terms
- Vitamin B6 deficiency
Excludes1 (do not code together)
- pyridoxine-responsive sideroblastic anemia (D64.3)
Where you may see this code
You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.
Related specialists
EndocrinologistGeneral Physician
Related codes
Sibling codes
Coverage-related procedures and services
CPT 11720high
DEBRIDEMENT OF NAIL(S) BY ANY METHOD(S); 1 TO 5
Source: CMS coverage guidance
CPT 11721high
DEBRIDEMENT OF NAIL(S) BY ANY METHOD(S); 6 OR MORE
Source: CMS coverage guidance
HCPCS G0127high
TRIMMING OF DYSTROPHIC NAILS, ANY NUMBER
Source: CMS coverage guidance
CPT 11719high
TRIMMING OF NONDYSTROPHIC NAILS, ANY NUMBER
Source: CMS coverage guidance
CPT 11056high
PARING OR CUTTING OF BENIGN HYPERKERATOTIC LESION (EG, CORN OR CALLUS); 2 TO 4 LESIONS
Source: CMS coverage guidance
CPT 11057high
PARING OR CUTTING OF BENIGN HYPERKERATOTIC LESION (EG, CORN OR CALLUS); MORE THAN 4 LESIONS
Source: CMS coverage guidance
Mapped diagnoses and classifications
SNOMED_CT 1144812004high
Inadequate intake of vitamin B6 and/or vitamin B6 derivative
Source: SNOMED International ICD-10 map
SNOMED_CT 230568001high
Neuropathy due to vitamin B6 deficiency
Source: SNOMED International ICD-10 map
SNOMED_CT 386080007high
Vitamin B6 deficiency
Source: SNOMED International ICD-10 map
SNOMED_CT 386081006high
Vitamin B6 deficiency (non anemic)
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy and official ICD code match exactly.
Legacy codes
E53.1
Common synonyms
Pyridoxine deficiency
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.