ICD10
ICD-10 Code E78.0: Pure hypercholesterolemia
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 entries help standardize how diagnoses are organized for coding, reporting, analytics, and documentation. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).
When is it used?
- May be used when a clinician documents pure hypercholesterolemia in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code may act more like a grouping or parent code, so a more specific child code may be used in final documentation when available.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
- This entry may represent a broader category rather than the most specific billable code.
Code hierarchy
chapter
4Endocrine, nutritional and metabolic diseases (E00-E89)
block
E70-E88Metabolic disorders
category
E78Disorders of lipoprotein metabolism and other lipidemias
currentE78
Where you may see this code
You may see this entry in coding references, medical records, or claims workflows when a broader diagnosis category is being reviewed before a more specific code is chosen.
Related specialists
EndocrinologistGeneral Physician
Related codes
Sibling codes
E78.1Pure hyperglyceridemiabillableE78.2Mixed hyperlipidemiabillableE78.3HyperchylomicronemiabillableE78.4Other hyperlipidemiaE78.5Hyperlipidemia, unspecifiedbillableE78.6Lipoprotein deficiencybillableE78.7Disorders of bile acid and cholesterol metabolismE78.8Other disorders of lipoprotein metabolismE78.9Disorder of lipoprotein metabolism, unspecifiedbillable
Mapped diagnoses and classifications
SNOMED_CT 767133009high
Double heterozygous familial hypercholesterolaemia
Source: SNOMED International ICD-10 map
SNOMED_CT 238081000high
Familial defective apolipoprotein B-100
Source: SNOMED International ICD-10 map
SNOMED_CT 398036000high
Familial hypercholesterolaemia
Source: SNOMED International ICD-10 map
SNOMED_CT 238079002high
Familial hypercholesterolaemia - heterozygous
Source: SNOMED International ICD-10 map
SNOMED_CT 403831006high
Familial hypercholesterolaemia due to genetic defect of apolipoprotein B
Source: SNOMED International ICD-10 map
SNOMED_CT 403829002high
Familial hypercholesterolaemia due to heterozygous LDL receptor mutation
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy code aligns to an official FY 2026 category. Frontend should resolve to the official category page and surface the billable child codes.
Legacy codes
E78.0
Replacement codes
E78.00 — Pure hypercholesterolemia, unspecified
Common synonyms
Pure hypercholesterolemia
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.