ICD10BillableValid for clinical use

ICD-10 Code E78.010: Homozygous familial hypercholesterolemia [HoFH]

E78.010 is a billable ICD-10 diagnosis code used to classify Homozygous familial hypercholesterolemia [HoFH] in medical records and claims. You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records. ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).

Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026

What is this code?

ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).

When is it used?

  • May be used when a clinician documents homozygous familial hypercholesterolemia [hofh] in a patient's medical record.
  • May appear in hospital records, claims, referrals, and clinical documentation.
  • This code can be used as a clinically usable diagnosis entry in standardized coding workflows.

What it does not mean

  • A code alone does not explain severity, treatment plan, or outcome.
  • A medical code should not be treated as a substitute for a doctor's diagnosis or advice.

Code hierarchy

chapter
4Endocrine, nutritional and metabolic diseases (E00-E89)
block
E70-E88Metabolic disorders
category
E78Disorders of lipoprotein metabolism and other lipidemias
category
E78.0Pure hypercholesterolemia
category
E78.01Familial hypercholesterolemia
currentE78.01

Where you may see this code

You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.

Related specialists

EndocrinologistGeneral Physician

Coverage-related procedures and services

Coding guidelines

Common synonyms

Homozygous familial hypercholesterolemia [HoFH]

Frequently asked questions

Code details

CodeE78.010
SystemICD10
Display nameHomozygous familial hypercholesterolemia [HoFH]
ChapterEndocrine, nutritional and metabolic diseases (E00-E89)
BlockMetabolic disorders

Flags

BillableYes
Valid clinical useYes

Source

SourceICD-10
Version2026-annual
Releaseannual
Year2026

Index terms

Matched terms
Cholesterolemia(essential) (pure)HoFH(homozygous familial hypercholesterolemia)Hypercholesterolemia(essential) (primary) (pure)

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

ICD-10 Code E78.010 for Homozygous familial hypercholesterolemia [HoFH] | HealthAssure