ICD10BillableValid for clinical use
ICD-10 Code E84.8: Cystic fibrosis with other manifestations
Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026
What is this code?
ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Endocrine, nutritional and metabolic diseases (E00-E89).
When is it used?
- May be used when a clinician documents cystic fibrosis with other manifestations in a patient's medical record.
- May appear in hospital records, claims, referrals, and clinical documentation.
- This code can be used as a clinically usable diagnosis entry in standardized coding workflows.
What it does not mean
- A code alone does not explain severity, treatment plan, or outcome.
- A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
Code hierarchy
chapter
4Endocrine, nutritional and metabolic diseases (E00-E89)
block
E70-E88Metabolic disorders
category
E84Cystic fibrosis
currentE84
Where you may see this code
You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.
Related specialists
EndocrinologistGeneral Physician
Related codes
Sibling codes
Coverage-related procedures and services
CPT 82306high
VITAMIN D; 25 HYDROXY, INCLUDES FRACTION(S), IF PERFORMED
Source: CMS coverage guidance
CPT 82652high
VITAMIN D; 1, 25 DIHYDROXY, INCLUDES FRACTION(S), IF PERFORMED
Source: CMS coverage guidance
CPT 81220high
CFTR (CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR) (EG, CYSTIC FIBROSIS) GENE ANALYSIS; COMMON VARIANTS (EG, ACMG/ACOG GUIDELINES)
Source: CMS coverage guidance
CPT 87428high
INFECTIOUS AGENT ANTIGEN DETECTION BY IMMUNOASSAY TECHNIQUE (EG, ENZYME IMMUNOASSAY [EIA], ENZYME-LINKED IMMUNOSORBENT ASSAY [ELISA], FLUORESCENCE IMMUNOASSAY [FIA], IMMUNOCHEMILUMINOMETRIC ASSAY [IMCA]), QUALITATIVE OR SEMIQUANTITATIVE; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS (EG, SARS-COV, SARS-COV-2 [COVID-19]) AND INFLUENZA VIRUS TYPES A AND B
Source: CMS coverage guidance
CPT 87631high
INFECTIOUS AGENT DETECTION BY NUCLEIC ACID (DNA OR RNA); RESPIRATORY VIRUS (EG, ADENOVIRUS, INFLUENZA VIRUS, CORONAVIRUS, METAPNEUMOVIRUS, PARAINFLUENZA VIRUS, RESPIRATORY SYNCYTIAL VIRUS, RHINOVIRUS), INCLUDES MULTIPLEX REVERSE TRANSCRIPTION, WHEN PERFORMED, AND MULTIPLEX AMPLIFIED PROBE TECHNIQUE, MULTIPLE TYPES OR SUBTYPES, 3-5 TARGETS
Source: CMS coverage guidance
CPT 87636high
INFECTIOUS AGENT DETECTION BY NUCLEIC ACID (DNA OR RNA); SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-COV-2) (CORONAVIRUS DISEASE [COVID-19]) AND INFLUENZA VIRUS TYPES A AND B, MULTIPLEX AMPLIFIED PROBE TECHNIQUE
Source: CMS coverage guidance
Mapped diagnoses and classifications
SNOMED_CT 698940002high
Arthropathy associated with cystic fibrosis
Source: SNOMED International ICD-10 map
SNOMED_CT 720401009high
Cystic fibrosis with gastritis and megaloblastic anemia syndrome
Source: SNOMED International ICD-10 map
SNOMED_CT 707536003high
Digestive system manifestation co-occurrent and due to cystic fibrosis
Source: SNOMED International ICD-10 map
SNOMED_CT 1335876002high
Early neonatal jaundice due to mucoviscidosis
Source: SNOMED International ICD-10 map
SNOMED_CT 707766007high
Exocrine pancreatic manifestation co-occurrent and due to cystic fibrosis
Source: SNOMED International ICD-10 map
SNOMED_CT 427022004high
Liver disease due to cystic fibrosis
Source: SNOMED International ICD-10 map
Coding guidelines
Compatibility
Legacy and official ICD code match exactly.
Legacy codes
E84.8
Common synonyms
Cystic fibrosis with other manifestations
Frequently asked questions
About this content
This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.