ICD10BillableValid for clinical use

ICD-10 Code I21.B: Myocardial infarction with coronary microvascular dysfunction

I21.B is a billable ICD-10 diagnosis code used to classify Myocardial infarction with coronary microvascular dysfunction in medical records and claims. You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records. ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Diseases of the circulatory system (I00-I99).

Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026

What is this code?

ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Diseases of the circulatory system (I00-I99).

When is it used?

  • May be used when a clinician documents myocardial infarction with coronary microvascular dysfunction in a patient's medical record.
  • May appear in hospital records, claims, referrals, and clinical documentation.
  • This code can be used as a clinically usable diagnosis entry in standardized coding workflows.

What it does not mean

  • A code alone does not explain severity, treatment plan, or outcome.
  • A medical code should not be treated as a substitute for a doctor's diagnosis or advice.

Code hierarchy

chapter
9Diseases of the circulatory system (I00-I99)
block
I20-I25Ischemic heart diseases
category
I21Acute myocardial infarction
currentI21

Official coding notes

Inclusion terms
  • Myocardial infarction with coronary microvascular disease
  • Myocardial infarction with nonobstructive coronary arteries [MINOCA] with microvascular disease

Where you may see this code

You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.

Related specialists

CardiologistGeneral Physician

Coverage-related procedures and services

CPT 93350high
ECHOCARDIOGRAPHY, TRANSTHORACIC, REAL-TIME WITH IMAGE DOCUMENTATION (2D), INCLUDES M-MODE RECORDING, WHEN PERFORMED, DURING REST AND CARDIOVASCULAR STRESS TEST USING TREADMILL, BICYCLE EXERCISE AND/OR PHARMACOLOGICALLY INDUCED STRESS, WITH INTERPRETATION AND REPORT;
Source: CMS coverage guidance
CPT 93351high
ECHOCARDIOGRAPHY, TRANSTHORACIC, REAL-TIME WITH IMAGE DOCUMENTATION (2D), INCLUDES M-MODE RECORDING, WHEN PERFORMED, DURING REST AND CARDIOVASCULAR STRESS TEST USING TREADMILL, BICYCLE EXERCISE AND/OR PHARMACOLOGICALLY INDUCED STRESS, WITH INTERPRETATION AND REPORT; INCLUDING PERFORMANCE OF CONTINUOUS ELECTROCARDIOGRAPHIC MONITORING, WITH SUPERVISION BY A PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROFESSIONAL
Source: CMS coverage guidance
CPT 0937Thigh
EXTERNAL ELECTROCARDIOGRAPHIC RECORDING FOR GREATER THAN 15 DAYS UP TO 30 DAYS BY CONTINUOUS RHYTHM RECORDING AND STORAGE; INCLUDING RECORDING, SCANNING ANALYSIS WITH REPORT, REVIEW AND INTERPRETATION BY A PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROFESSIONAL
Source: CMS coverage guidance
CPT 0938Thigh
EXTERNAL ELECTROCARDIOGRAPHIC RECORDING FOR GREATER THAN 15 DAYS UP TO 30 DAYS BY CONTINUOUS RHYTHM RECORDING AND STORAGE; RECORDING (INCLUDING CONNECTION AND INITIAL RECORDING)
Source: CMS coverage guidance
CPT 0940Thigh
EXTERNAL ELECTROCARDIOGRAPHIC RECORDING FOR GREATER THAN 15 DAYS UP TO 30 DAYS BY CONTINUOUS RHYTHM RECORDING AND STORAGE; REVIEW AND INTERPRETATION BY A PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROFESSIONAL
Source: CMS coverage guidance
CPT 0939Thigh
EXTERNAL ELECTROCARDIOGRAPHIC RECORDING FOR GREATER THAN 15 DAYS UP TO 30 DAYS BY CONTINUOUS RHYTHM RECORDING AND STORAGE; SCANNING ANALYSIS WITH REPORT
Source: CMS coverage guidance

Coding guidelines

Common synonyms

Myocardial infarction with coronary microvascular dysfunction

Frequently asked questions

Code details

CodeI21.B
SystemICD10
Display nameMyocardial infarction with coronary microvascular dysfunction
ChapterDiseases of the circulatory system (I00-I99)
BlockIschemic heart diseases

Flags

BillableYes
Valid clinical useYes

Source

SourceICD-10
Version2026-annual
Releaseannual
Year2026

Index terms

Matched terms
Disease, diseasedDysfunctionInfarct, infarctionInfarct, infarctionInfarct, infarction

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

ICD-10 Code I21.B for Myocardial infarction with coronary microvascular dysfunction | HealthAssure