ICD10BillableValid for clinical use

ICD-10 Code O21.1: Hyperemesis gravidarum with metabolic disturbance

O21.1 is a billable ICD-10 diagnosis code used to classify Hyperemesis gravidarum with metabolic disturbance in medical records and claims. You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records. ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Pregnancy, childbirth and the puerperium (O00-O9A).

Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026

What is this code?

ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Pregnancy, childbirth and the puerperium (O00-O9A).

When is it used?

  • May be used when a clinician documents hyperemesis gravidarum with metabolic disturbance in a patient's medical record.
  • May appear in hospital records, claims, referrals, and clinical documentation.
  • This code can be used as a clinically usable diagnosis entry in standardized coding workflows.

What it does not mean

  • A code alone does not explain severity, treatment plan, or outcome.
  • A medical code should not be treated as a substitute for a doctor's diagnosis or advice.

Code hierarchy

chapter
15Pregnancy, childbirth and the puerperium (O00-O9A)
block
O20-O29Other maternal disorders predominantly related to pregnancy
category
O21Excessive vomiting in pregnancy
currentO21

Official coding notes

Inclusion terms
  • Hyperemesis gravidarum, starting before the end of the 20th week of gestation, with metabolic disturbance such as carbohydrate depletion
  • Hyperemesis gravidarum, starting before the end of the 20th week of gestation, with metabolic disturbance such as dehydration
  • Hyperemesis gravidarum, starting before the end of the 20th week of gestation, with metabolic disturbance such as electrolyte imbalance

Where you may see this code

You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.

Related specialists

ObstetricianGynecologistEndocrinologist

Coverage-related procedures and services

Coding guidelines

Compatibility

Legacy and official ICD code match exactly.
Legacy codes
O21.1

Common synonyms

Hyperemesis gravidarum with metabolic disturbance

Frequently asked questions

Code details

CodeO21.1
SystemICD10
Display nameHyperemesis gravidarum with metabolic disturbance
ChapterPregnancy, childbirth and the puerperium (O00-O9A)
BlockOther maternal disorders predominantly related to pregnancy

Flags

BillableYes
Valid clinical useYes

Source

SourceICD-10
Version2026-annual
Releaseannual
Year2026

Index terms

Matched terms
HyperemesisHyperemesisHyperemesisHyperemesisHyperemesisImbalance

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

ICD-10 Code O21.1 for Hyperemesis gravidarum with metabolic disturbance | HealthAssure