ICD10BillableValid for clinical use

ICD-10 Code R16.1: Splenomegaly, not elsewhere classified

R16.1 is a billable ICD-10 diagnosis code used to classify Splenomegaly, not elsewhere classified in medical records and claims. You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records. ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99).

Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026

What is this code?

ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99).

When is it used?

  • May be used when a clinician documents splenomegaly, not elsewhere classified in a patient's medical record.
  • May appear in hospital records, claims, referrals, and clinical documentation.
  • This code can be used as a clinically usable diagnosis entry in standardized coding workflows.

What it does not mean

  • A code alone does not explain severity, treatment plan, or outcome.
  • A medical code should not be treated as a substitute for a doctor's diagnosis or advice.

Code hierarchy

chapter
18Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)
block
R10-R19Symptoms and signs involving the digestive system and abdomen
category
R16Hepatomegaly and splenomegaly, not elsewhere classified
currentR16

Official coding notes

Inclusion terms
  • Splenomegaly NOS

Where you may see this code

You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.

Related specialists

General Physician

Coverage-related procedures and services

CPT 81450high
HEMATOLYMPHOID NEOPLASM OR DISORDER, GENOMIC SEQUENCE ANALYSIS PANEL, 5-50 GENES, INTERROGATION FOR SEQUENCE VARIANTS, AND COPY NUMBER VARIANTS OR REARRANGEMENTS, OR ISOFORM EXPRESSION OR MRNA EXPRESSION LEVELS, IF PERFORMED; DNA ANALYSIS OR COMBINED DNA AND RNA ANALYSIS
Source: CMS coverage guidance
CPT 81451high
HEMATOLYMPHOID NEOPLASM OR DISORDER, GENOMIC SEQUENCE ANALYSIS PANEL, 5-50 GENES, INTERROGATION FOR SEQUENCE VARIANTS, AND COPY NUMBER VARIANTS OR REARRANGEMENTS, OR ISOFORM EXPRESSION OR MRNA EXPRESSION LEVELS, IF PERFORMED; RNA ANALYSIS
Source: CMS coverage guidance
CPT 81479high
UNLISTED MOLECULAR PATHOLOGY PROCEDURE
Source: CMS coverage guidance
CPT 93975high
DUPLEX SCAN OF ARTERIAL INFLOW AND VENOUS OUTFLOW OF ABDOMINAL, PELVIC, SCROTAL CONTENTS AND/OR RETROPERITONEAL ORGANS; COMPLETE STUDY
Source: CMS coverage guidance
CPT 93976high
DUPLEX SCAN OF ARTERIAL INFLOW AND VENOUS OUTFLOW OF ABDOMINAL, PELVIC, SCROTAL CONTENTS AND/OR RETROPERITONEAL ORGANS; LIMITED STUDY
Source: CMS coverage guidance
CPT 88182high
FLOW CYTOMETRY, CELL CYCLE OR DNA ANALYSIS
Source: CMS coverage guidance

Coding guidelines

Compatibility

Legacy and official ICD code match exactly.
Legacy codes
R16.1

Common synonyms

Splenomegaly, not elsewhere classified

Frequently asked questions

Code details

CodeR16.1
SystemICD10
Display nameSplenomegaly, not elsewhere classified
ChapterSymptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)
BlockSymptoms and signs involving the digestive system and abdomen

Flags

BillableYes
Valid clinical useYes

Source

SourceICD-10
Version2026-annual
Releaseannual
Year2026

Index terms

Matched terms
Disease, diseasedDébove's disease(splenomegaly)MassSplenomegaly, splenomegalia(Bengal) (cryptogenic) (idiopathic) (tropical)

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

ICD-10 Code R16.1 for Splenomegaly, not elsewhere classified | HealthAssure