What does ICD-10 code R77 mean?

ICD-10 code R77 is the standardized code used for other abnormalities of plasma proteins in medical records and coding systems.

When is ICD-10 code R77 used?

Doctors, hospitals, and insurers may use ICD-10 code R77 when recording other abnormalities of plasma proteins in a standardized format. This entry may also act as a broader category that points toward more specific child codes.

Does ICD-10 code R77 confirm a diagnosis?

No. A code helps standardize documentation and claims, but it should not be read as a substitute for a clinician's full assessment.

ICD10

ICD-10 Code R77: Other abnormalities of plasma proteins

Name: ICD-10 Code R77: Other abnormalities of plasma proteins
Creator: HealthAssure Clinical Team
Published: 2026-05-21T06:30:48.930Z

R77 is an ICD-10 diagnosis entry used to group records related to Other abnormalities of plasma proteins. You may see this entry in coding references, medical records, or claims workflows when a broader diagnosis category is being reviewed before a more specific code is chosen. ICD-10 entries help standardize how diagnoses are organized for coding, reporting, analytics, and documentation. This code sits within the broader ICD-10 area for Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99).

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

ICD-10 entries help standardize how diagnoses are organized for coding, reporting, analytics, and documentation. This code sits within the broader ICD-10 area for Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99).

When is it used?

May be used when a clinician documents other abnormalities of plasma proteins in a patient's medical record.
May appear in hospital records, claims, referrals, and clinical documentation.
This code may act more like a grouping or parent code, so a more specific child code may be used in final documentation when available.

What it does not mean

A code alone does not explain severity, treatment plan, or outcome.
A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
This entry may represent a broader category rather than the most specific billable code.

Code hierarchy

chapter

18Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)

block

R70-R79Abnormal findings on examination of blood, without diagnosis

currentR70-R79

Official coding notes

Excludes1 (do not code together)

disorders of plasma-protein metabolism (E88.0-)

Where you may see this code

You may see this entry in coding references, medical records, or claims workflows when a broader diagnosis category is being reviewed before a more specific code is chosen.

Related specialists

General Physician

Sibling codes

R70Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity R71Abnormality of red blood cells R73Elevated blood glucose level R74Abnormal serum enzyme levels R75Inconclusive laboratory evidence of human immunodeficiency virus [HIV]billable R76Other abnormal immunological findings in serum R78Findings of drugs and other substances, not normally found in blood R79Other abnormal findings of blood chemistry

Coding guidelines

Compatibility

Legacy code aligns to an official FY 2026 category. Frontend should resolve to the official category page and surface the billable child codes.

Legacy codes

R77

Replacement codes

R77.0 — Abnormality of albuminR77.1 — Abnormality of globulinR77.2 — Abnormality of alphafetoproteinR77.8 — Other specified abnormalities of plasma proteinsR77.9 — Abnormality of plasma protein, unspecified

Common synonyms

Other abnormalities of plasma proteins

Frequently asked questions

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.