ICD10

ICD-10 Code T80.91: Hemolytic transfusion reaction, unspecified incompatibility

T80.91 is an ICD-10 diagnosis entry used to group records related to Hemolytic transfusion reaction, unspecified incompatibility. You may see this entry in coding references, medical records, or claims workflows when a broader diagnosis category is being reviewed before a more specific code is chosen. ICD-10 entries help standardize how diagnoses are organized for coding, reporting, analytics, and documentation. This code sits within the broader ICD-10 area for Injury, poisoning and certain other consequences of external causes (S00-T88).

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

ICD-10 entries help standardize how diagnoses are organized for coding, reporting, analytics, and documentation. This code sits within the broader ICD-10 area for Injury, poisoning and certain other consequences of external causes (S00-T88).

When is it used?

  • May be used when a clinician documents hemolytic transfusion reaction, unspecified incompatibility in a patient's medical record.
  • May appear in hospital records, claims, referrals, and clinical documentation.
  • This code may act more like a grouping or parent code, so a more specific child code may be used in final documentation when available.

What it does not mean

  • A code alone does not explain severity, treatment plan, or outcome.
  • A medical code should not be treated as a substitute for a doctor's diagnosis or advice.
  • This entry may represent a broader category rather than the most specific billable code.

Code hierarchy

chapter
19Injury, poisoning and certain other consequences of external causes (S00-T88)
block
T07-T88Injury, poisoning and certain other consequences of external causes
block
T80-T88Complications of surgical and medical care, not elsewhere classified
category
T80Complications following infusion, transfusion and therapeutic injection
category
T80.9Unspecified complication following infusion, transfusion and therapeutic injection
currentT80.9

Official coding notes

Excludes1 (do not code together)
  • ABO incompatibility with hemolytic transfusion reaction (T80.31-)
  • Non-ABO incompatibility with hemolytic transfusion reaction (T80.A1-)
  • Rh incompatibility with hemolytic transfusion reaction (T80.41-)

Where you may see this code

You may see this entry in coding references, medical records, or claims workflows when a broader diagnosis category is being reviewed before a more specific code is chosen.

Related specialists

Emergency Medicine SpecialistOrthopedic Specialist

Coding guidelines

Common synonyms

Hemolytic transfusion reaction, unspecified incompatibilityHemolytic transfusion reaction

Frequently asked questions

Code details

CodeT80.91
SystemICD10
Display nameHemolytic transfusion reaction, unspecified incompatibility
ChapterInjury, poisoning and certain other consequences of external causes (S00-T88)
BlockComplications of surgical and medical care, not elsewhere classified

Flags

BillableNo
Valid clinical useNo

Source

SourceICD-10
Version2026-annual
Releaseannual
Year2026

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

ICD-10 Code T80.91 for Hemolytic transfusion reaction, unspecified incompatibility | HealthAssure