What does ICD-10 code Z17.22 mean?

ICD-10 code Z17.22 is the standardized code used for progesterone receptor negative status in medical records and coding systems.

When is ICD-10 code Z17.22 used?

Doctors, hospitals, and insurers may use ICD-10 code Z17.22 when recording progesterone receptor negative status in a standardized format.

Does ICD-10 code Z17.22 confirm a diagnosis?

No. A code helps standardize documentation and claims, but it should not be read as a substitute for a clinician's full assessment.

ICD10BillableValid for clinical use

ICD-10 Code Z17.22: Progesterone receptor negative status

Name: ICD-10 Code Z17.22: Progesterone receptor negative status
Creator: HealthAssure Clinical Team
Published: 2026-05-21T06:50:26.384Z

Z17.22 is a billable ICD-10 diagnosis code used to classify Progesterone receptor negative status in medical records and claims. You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records. ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Factors influencing health status and contact with health services (Z00-Z99).

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Factors influencing health status and contact with health services (Z00-Z99).

When is it used?

May be used when a clinician documents progesterone receptor negative status in a patient's medical record.
May appear in hospital records, claims, referrals, and clinical documentation.
This code can be used as a clinically usable diagnosis entry in standardized coding workflows.

What it does not mean

A code alone does not explain severity, treatment plan, or outcome.
A medical code should not be treated as a substitute for a doctor's diagnosis or advice.

Code hierarchy

chapter

21Factors influencing health status and contact with health services (Z00-Z99)

block

Z17Estrogen, and other hormones and factors receptor status (Z17)

Official coding notes

Inclusion terms

Where you may see this code

You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.

Related specialists

General Physician

Sibling codes

Z17.21Progesterone receptor positive statusbillable

Coding guidelines

Common synonyms

Progesterone receptor negative status

Frequently asked questions

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.