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ICD10BillableValid for clinical use

ICD-10 Code Z79.818: Long term (current) use of other agents affecting estrogen receptors and estrogen levels

Z79.818 is a billable ICD-10 diagnosis code used to classify Long term (current) use of other agents affecting estrogen receptors and estrogen levels in medical records and claims. You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records. ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Factors influencing health status and contact with health services (Z00-Z99).

Reviewed by HealthAssure Clinical TeamUpdated 26 May 2026

What is this code?

ICD-10 codes are diagnosis classification codes used in healthcare records, reporting, coding workflows, and billing support. This code sits within the broader ICD-10 area for Factors influencing health status and contact with health services (Z00-Z99).

When is it used?

  • May be used when a clinician documents long term (current) use of other agents affecting estrogen receptors and estrogen levels in a patient's medical record.
  • May appear in hospital records, claims, referrals, and clinical documentation.
  • This code can be used as a clinically usable diagnosis entry in standardized coding workflows.

What it does not mean

  • A code alone does not explain severity, treatment plan, or outcome.
  • A medical code should not be treated as a substitute for a doctor's diagnosis or advice.

Code hierarchy

chapter
21Factors influencing health status and contact with health services (Z00-Z99)
block
Z77-Z99Persons with potential health hazards related to family and personal history and certain conditions influencing health status
category
Z79Long term (current) drug therapy
category
Z79.8Other long term (current) drug therapy
category
Z79.81Long term (current) use of agents affecting estrogen receptors and estrogen levels
currentZ79.81

Official coding notes

Inclusion terms
  • Long term (current) use of estrogen receptor downregulators
  • Long term (current) use of fulvestrant (Faslodex)
  • Long term (current) use of gonadotropin-releasing hormone (GnRH) agonist
  • Long term (current) use of goserelin acetate (Zoladex)
  • Long term (current) use of leuprolide acetate (leuprorelin) (Lupron)
  • Long term (current) use of megestrol acetate (Megace)

Where you may see this code

You may see this code in hospital records, discharge summaries, insurance claims, encounter documentation, referrals, or other healthcare billing and coding records.

Related specialists

General Physician

Coverage-related procedures and services

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Source: CMS coverage guidance
CPT 78350high
BONE DENSITY (BONE MINERAL CONTENT) STUDY, 1 OR MORE SITES; SINGLE PHOTON ABSORPTIOMETRY
Source: CMS coverage guidance
CPT 82652high
VITAMIN D; 1, 25 DIHYDROXY, INCLUDES FRACTION(S), IF PERFORMED
Source: CMS coverage guidance
CPT 82306high
VITAMIN D; 25 HYDROXY, INCLUDES FRACTION(S), IF PERFORMED
Source: CMS coverage guidance
CPT 0556Thigh
BONE STRENGTH AND FRACTURE RISK USING FINITE ELEMENT ANALYSIS OF FUNCTIONAL DATA AND BONE-MINERAL DENSITY UTILIZING DATA FROM A COMPUTED TOMOGRAPHY SCAN; ASSESSMENT OF BONE STRENGTH AND FRACTURE RISK AND BONE-MINERAL DENSITY
Source: CMS coverage guidance
CPT 0557Thigh
BONE STRENGTH AND FRACTURE RISK USING FINITE ELEMENT ANALYSIS OF FUNCTIONAL DATA AND BONE-MINERAL DENSITY UTILIZING DATA FROM A COMPUTED TOMOGRAPHY SCAN; INTERPRETATION AND REPORT
Source: CMS coverage guidance

Coding guidelines

Common synonyms

Long term (current) use of other agents affecting estrogen receptors and estrogen levelsLong termLong term current use of other agents affecting estrogen receptors and estrogen levels

Frequently asked questions

Code details

CodeZ79.818
SystemICD10
Display nameLong term (current) use of other agents affecting estrogen receptors and estrogen levels
ChapterFactors influencing health status and contact with health services (Z00-Z99)
BlockPersons with potential health hazards related to family and personal history and certain conditions influencing health status

Flags

BillableYes
Valid clinical useYes

Source

SourceICD-10
Version2026-annual
Releaseannual
Year2026

Index terms

Matched terms
Long-term(current) (prophylactic) drug therapy (use of)Long-term(current) (prophylactic) drug therapy (use of)Long-term(current) (prophylactic) drug therapy (use of)Long-term(current) (prophylactic) drug therapy (use of)Long-term(current) (prophylactic) drug therapy (use of)Long-term(current) (prophylactic) drug therapy (use of)Long-term(current) (prophylactic) drug therapy (use of)TherapyTherapyTherapyTherapyTherapy

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from ICD-10. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.