What does this LOINC code represent?

This LOINC code identifies a lab observation, measurement, question, or clinical concept in a standardized format.

Is this enough to understand my test result?

No. The code identifies the test or observation, but the interpretation depends on the actual result, reference range, and clinical context.

LOINCActiveBoth

LOINC Code 101281-4: Neurofilament light chain IA [Mass/Vol]

Name: LOINC Code 101281-4: Neurofilament light chain IA [Mass/Vol]
Creator: HealthAssure Clinical Team
Published: 2026-05-21T11:17:17.027Z

101281-4 is a LOINC code used to identify Neurofilament light chain IA [Mass/Vol] in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Neurofilament light chain. It is commonly used with the system or sample type Ser/Plas.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Neurofilament light chain. It is commonly used with the system or sample type Ser/Plas.

When is it used?

Used in lab systems, EHRs, and clinical data exchange.
May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
Status: ACTIVE
Order vs observation: Both
Method: IA

What it does not mean

The code identifies the observation or test, not the actual result.

Key facts

Neurofilament light chain [Mass/volume] in Serum or Plasma by Immunoassay
Neurofilament light chain
Chains; Chemistry; Chn; EIA; ELFA; ELISA; Enzyme immunoassay; IAA; Level; Mass concentration; MEIA; NfL; Nfl chain; Pl; Plasma; Plsm; Point in time; QNT; Quan; Quant; Quantitative; Random; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; SUDS

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Neurofilament light chain IA [Mass/Vol]Neurofilament light chain [Mass/volume] in Serum or Plasma by ImmunoassayNfl chain SerPl IA-mCncNeurofilament light chainCHEMNeurofilament light chain, BloodMCnc

Frequently asked questions

Code details

Code101281-4

SystemLOINC

Display nameNeurofilament light chain IA [Mass/Vol]

DescriptionNeurofilament light chain

Short nameNfl chain SerPl IA-mCnc

ComponentNeurofilament light chain

PropertyMCnc

TimingPt

System (specimen)Ser/Plas

ScaleQn

MethodIA

ClassCHEM

Example unitspg/mL

StatusACTIVE

Order/ObservationBoth

Flags

BillableNo

Valid clinical useNo

Source

SourceLOINC

Version2.82

Releasemain

First released2.74

Last changed2.75

Consumer names

Neurofilament light chain, Blood

Part names

Neurofilament light chainMCncPtSer/PlasQnIAMass ConcentrationPoint in time (spot)Serum or PlasmaImmunoassay

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.