LOINCActive

LOINC Code 21995-6: Siteandtype override flag Cancer case

21995-6 is a LOINC code used to identify Siteandtype override flag Cancer case in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Site&type override flag. It is commonly used with the system or sample type Cancer case.XXX.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Site&type override flag. It is commonly used with the system or sample type Cancer case.XXX.

When is it used?

  • Used in lab systems, EHRs, and clinical data exchange.
  • May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
  • Status: ACTIVE

What it does not mean

  • The code identifies the observation or test, not the actual result.

Key facts

Siteandtype override flag Cancer case
Site&type override flag
Some computer edits identify errors. Others indicate possible errors that require manual review for resolution. To eliminate the need to review the same cases repeatedly, over-ride flags have been developed to indicate that data in a record (or records) have been reviewed and, while unusual, are correct. This over-ride is used with the following edits in the NAACCR Metafile of the EDITS softwarePrimary Site, Morphology-Type Check (SEER IF25) Primary Site, Morphology-Type Check ICDO3 (SEER IF25) Some edits check for code combinations that are possible, but quite rare. If the code combination generates an error message and review of the case indicates that the codes are correct for the case then the over-ride flag is used to skip the edit in the future. See Chapter IV, Recommended Data Edits and Software Coordination of Standards. Over-ride Flag as Used in the EDITS Software Package Multiple versions of edits of the type Primary site, Morphology-Type check for "usual" combinations of site and ICD-O-2 or ICD-O-3 histology. The SEER version of the edit is more restrictive than the COC edit, and thus uses a different over-ride flag. The COC version of the edit will accept Over-ride COC-Site/Type or Over-ride Site/Type as equivalent. The Site/Histology validation list (available on the SEER web site) contains those histologies commonly found in the specified primary site. Histologies that occur only rarely or never are not included. These edits require review of all combinations not listed. Since basal and squamous cell carcinomas of non-genital skin sites are not reportable to SEER, these site/histology combinations do not appear on the SEER validation list. For the COC version of the edit, if Primary Site is in the rage C440-C449 (skin), and Histologic Type ICD-O-3 is in the range 8000-8005 (neoplasms, malignant, NOS), 8010-8046 (epithelial carcinomas), 8050-8084 (papillary and squamous cell carcinomas), or 8090-8110 (basal cell carcinomas), no further editing is done. No over-ride is necessary for these cases in the COC version of the edit. Review of these cases requires investigating whether a) the combination is biologically implausible, or b) there are cancer registry coding conventions that would dictate different codes for the diagnosis. Review of these rare combinations often results in changes to the primary site and/or morphology, rather than a decision that the combination is correct. Instructions for Coding Leave blank if the program does not generate an error message for the edit Primary Site, Morphology-Type Check (SEER IF25) and/or the edit Primary Site, Morphology-Type ICDO3 (SEERIF25). Leave blank and correct any errors for the case if an item is discovered to be incorrect. Code 1 if the case has been reviewed and both the site and histology are correct... NAACCR Data Standards and Data Dictionary Version 11
Arbitrary; CA; Misc; Miscellaneous; Oncology; Ordinal; Other; Point in time; QL; Qual; Qualitative; Random; Screen; Site/type O/R; Spec; To be specified in another part of the message; TUMOR REGISTRY(NAACCR); Unspecified

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Siteandtype override flag Cancer caseSite/type O/R Cancer caseSite&type override flagTUMRRGTArbPtCancer case.XXX

Frequently asked questions

Code details

Code21995-6
SystemLOINC
Display nameSiteandtype override flag Cancer case
DescriptionSite&type override flag
Short nameSite/type O/R Cancer case
ComponentSite&type override flag
PropertyArb
TimingPt
System (specimen)Cancer case.XXX
ScaleOrd
ClassTUMRRGT
StatusACTIVE

Flags

BillableNo
Valid clinical useNo

Source

SourceLOINC
Version2.82
Releasemain
First released1.0m
Last changed2.38

Part names

Site&type override flagArbPtCancer case.XXXOrdSiteandtype override flagArbitraryPoint in time (spot)Cancer case XXX

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

LOINC Code 21995-6 | HealthAssure