What does this LOINC code represent?

This LOINC code identifies a lab observation, measurement, question, or clinical concept in a standardized format.

Is this enough to understand my test result?

No. The code identifies the test or observation, but the interpretation depends on the actual result, reference range, and clinical context.

LOINCActive

LOINC Code 22000-4: Site and behavior override flag Cancer case

Name: LOINC Code 22000-4: Site and behavior override flag Cancer case
Creator: HealthAssure Clinical Team
Published: 2026-05-21T11:17:30.108Z

22000-4 is a LOINC code used to identify Site and behavior override flag Cancer case in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Site & behavior override flag. It is commonly used with the system or sample type Cancer case.XXX.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Site & behavior override flag. It is commonly used with the system or sample type Cancer case.XXX.

When is it used?

Used in lab systems, EHRs, and clinical data exchange.
May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
Status: ACTIVE

What it does not mean

The code identifies the observation or test, not the actual result.

Key facts

Site and behavior override flag Cancer case

Site & behavior override flag

Some computer edits identify errors. Others indicate possible errors that require manual review for resolution. To eliminate the need to review the same cases repeatedly, over-ride flags have been developed to indicate that data in a record (or records) have been reviewed and, while unusual, are correct. This over-ride is used with the following edits in the NAACCR Metafile of the EDITS softwarePrimary Site, Behavior Code (COC) Primary Site, Behavior Code (SEER IF39) Primary Site, Behavior Code ICDO3 (COC) Primary Site, Behavior Code ICDO3 (SEER IF39) Some edits check for code combinations that are possible, but quite rare. If the code combination generates an error message and review of the case indicates that the codes are correct for the case, then the over-ride flag is used to skip the edit in the future. See Chapter IV, Recommended Data Edits and Software Coordination of Standards. Over-ride Flag as Used in the EDITS Software Package Edits of the type, Primary Site, Behavior Code, require review of the following primary sites with a behavior of in situ (ICD-O-2 or ICD-O-3 behavior = 2): C269 Gastrointestinal tract, NOS C399 Ill-defined sites within respiratory system C559 Uterus, NOS C579 Female genital tract, NOS C639 Male genital organs, NOS C689 Urinary system, NOS C729 Nervous system, NOS C759 Endocrine gland, NOS C760-C768 Ill-defined sites C809 Unknown primary site Since the designation of in situ is very specific and almost always requires microscopic confirmation, ordinarily specific information should also be available regarding the primary site. Conversely, if inadequate information is available to determine a specific primary site, it is unlikely that information about a cancer being in situ is reliable. If an in situ diagnosis is stated, try to obtain a more specific primary site. A primary site within an organ system can sometimes be identified based on the diagnostic procedure or treatment given or on the histologic type. If no more specific site can be determined, it is usually preferable to code a behavior code of 3. In the exceedingly rare situation in which it is certain that the behavior is in situ and no more specific site code is applicable, set Over-ride Site/Behavior to 1. Instructions for Coding Leave blank if the program does not generate an error message for the edit Primary Site, Behavior Code (COC) and/or the edit Primary Site, Behavior Code ICD-O-3 (COC). Leave blank and correct any errors for the case if an item is discovered to be incorrect. Code 1 if review of site and behavior verifies that the patient has an in situ cancer of a nonspecific site and no further information about the primary site is available... NAACCR Data Standards and Data Dictionary Version 11

Arbitrary; CA; Misc; Miscellaneous; Oncology; Ordinal; Other; Point in time; QL; Qual; Qualitative; Random; Screen; Site/Behavior O/R; Spec; To be specified in another part of the message; TUMOR REGISTRY(NAACCR); Unspecified

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Site and behavior override flag Cancer caseSite/Behavior O/R Cancer caseSite & behavior override flagTUMRRGTArbPtCancer case.XXX

Frequently asked questions

Code details

Code22000-4

SystemLOINC

Display nameSite and behavior override flag Cancer case

DescriptionSite & behavior override flag

Short nameSite/Behavior O/R Cancer case

ComponentSite & behavior override flag

PropertyArb

TimingPt

System (specimen)Cancer case.XXX

ScaleOrd

ClassTUMRRGT

StatusACTIVE

Flags

BillableNo

Valid clinical useNo

Source

SourceLOINC

Version2.82

Releasemain

First released1.0m

Last changed2.38

Part names

Site & behavior override flagArbPtCancer case.XXXOrdSite and behavior override flagArbitraryPoint in time (spot)Cancer case XXX

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.