LOINC Code 49029-2: Cortisol Free/Cortisone free (U) [Mass ratio]

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Cortisol.free/Cortisone.free. It is commonly used with the system or sample type Urine.

When is it used?

• Used in lab systems, EHRs, and clinical data exchange.
• May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
• Status: ACTIVE
• Order vs observation: Both

What it does not mean

• The code identifies the observation or test, not the actual result.

Key facts

• Cortisol Free/Cortisone free [Mass Ratio] in Urine
• Cortisol.free/Cortisone.free
• Determining the ratio of urinary-free cortisol to cortisone is useful in evaluating patients with apparent mineralocorticoid excess (AME) syndrome and other forms of adrenal insufficiency. Higher ratios are observed in patients with AME syndrome and indicate insufficient levels of 11-beta-hydroxy steroid dehydrogenase type 2 (11-beta HSD2), which converts cortisol to cortisone. Lower ratios suggests low activity of the 11-beta-HSD1 enzyme, which converts cortisone to cortisol, and may explain reduced effectiveness of cortisone treatment.
• 11-beta HSD; 11-beta-HSD1; 11-beta-HSD2; 11-beta-hydroxy steroid dehydrogenase; 11-ß-HSD1; 11-ß-HSD2; 17-Hydroxycorticosterone; c155; Chemistry; Compound E; Compound F; Coritsol; Cort; Cortis F; Cortisone free; F; FR; hydrocortisone; Mass concentration ratio; Mass ratio; MCRto; Non-protein bound; Point in time; QNT; Quan; Quant; Quantitative; Random; UA; UR; Urn

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Related SNOMED CT concepts

Related observations and tests

Common synonyms

Frequently asked questions