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LOINC Code 53711-8: Neuronal nuclear type 1 Ab (CSF) [Titer]

53711-8 is a LOINC code used to identify Neuronal nuclear type 1 Ab (CSF) [Titer] in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Neuronal nuclear type 1 Ab. It is commonly used with the system or sample type CSF.

Reviewed by HealthAssure Clinical TeamUpdated 25 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Neuronal nuclear type 1 Ab. It is commonly used with the system or sample type CSF.

When is it used?

  • Used in lab systems, EHRs, and clinical data exchange.
  • May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
  • Status: ACTIVE
  • Order vs observation: Both

What it does not mean

  • The code identifies the observation or test, not the actual result.

Key facts

Neuronal nuclear type 1 Ab [Titer] in Cerebral spinal fluid
Neuronal nuclear type 1 Ab
Anti-Neuronal Nuclear Antibody Type 1 Cerebrospinal fluid (CSF) titer. This antibody recognizes a 35-40 kD component found in neuronal cell nuclei. ANNA-1 antibody is found almost exclusively in patients with a history of tobacco use or passive exposure. Women are affected twice as often as men. Cancer has been found in more than 90% of seropositive patients. Small cell lung carcinoma (SCLC) has been found in 80% of patients. A second malignant neoplasm is found in 13% of patients positive for ANNA-1 who have SCLC. The most common clinical presentation of patients positive for ANNA-1 is peripheral neuropathy, but they can exhibit any element of encephalomyeloradiculopathy. About 10% of patients present with gastroparesis or intestinal obstruction. ANNA-1 has also been detected in children with intestinal dysmotility, cerbellar ataxia, and brainstem encephalitis with and without neuroblastoma. It is detected in 5 to 10% of patients with SCLC who do not have a paraneoplastic syndrome. Paraneoplastic syndromes are autoantibody-mediated neurologic disorders associated with underlying tumors. These syndromes arise when systemic tumors express antigens normally found only in neural tissue. Serum is the preferred specimen. CSF results are sometimes positive when serum results are negative. If a lumbar puncture is going to be performed as part of the diagnostic workup, CSF testing is recommended to improve the detection rate. Information from http//www.clinlabnavigator.com accessed 2008 15 02.
ABS; Aby; ANNA 1; ANNA-1; Antby; Anti; Antibodies; Antibody; Autoantibodies; Autoantibody; Cerebral spinal fluid; Cerebrospinal Fl; Dilution factor; Dilution Factor (Titer); Hu; Hu1; i; Neuro; Neurology; Neuronal nuclear type I; Nuc; Paraneoplastic syndrome; Point in time; Random; Serology; SmQn; Spinal Fl; Spinal Fld; Spinal Flu; Spinal Fluid; Titer; Titered; Titre; Ttr

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Neuronal nuclear type 1 Ab (CSF) [Titer]Neuronal nuclear type 1 Ab [Titer] in Cerebral spinal fluidHu1 Ab Titr CSFNeuronal nuclear type 1 AbSERONeuronal nuclear type 1 antibody, Spinal fluidTitr

Frequently asked questions

Code details

Code53711-8
SystemLOINC
Display nameNeuronal nuclear type 1 Ab (CSF) [Titer]
DescriptionNeuronal nuclear type 1 Ab
Short nameHu1 Ab Titr CSF
ComponentNeuronal nuclear type 1 Ab
PropertyTitr
TimingPt
System (specimen)CSF
ScaleSemiQn
ClassSERO
Example unitstiter
StatusACTIVE
Order/ObservationBoth

Flags

BillableNo
Valid clinical useNo

Source

SourceLOINC
Version2.82
Releasemain
First released2.26
Last changed2.75

Consumer names

Neuronal nuclear type 1 antibody, Spinal fluid

Part names

Neuronal nuclear type 1 AbTitrPtCSFSemiQnTiterPoint in time (spot)Cerebral spinal fluid

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

LOINC Code 53711-8 | HealthAssure