LOINCActiveObservation

LOINC Code 66880-6: Skin Ab.IgG pattern Monkey esophagus substrate (S) [Interp]

66880-6 is a LOINC code used to identify Skin Ab.IgG pattern Monkey esophagus substrate (S) [Interp] in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Skin Ab.IgG pattern. It is commonly used with the system or sample type Ser.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Skin Ab.IgG pattern. It is commonly used with the system or sample type Ser.

When is it used?

  • Used in lab systems, EHRs, and clinical data exchange.
  • May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
  • Status: ACTIVE
  • Order vs observation: Observation
  • Method: Monkey esophagus substrate

What it does not mean

  • The code identifies the observation or test, not the actual result.

Key facts

  • Skin Ab.IgG pattern [Interpretation] in Serum by Monkey esophagus substrate
  • Skin Ab.IgG pattern
  • The detection of skin antibodies assists in the diagnosis of chronic vesicular-bullous diseases such as pemphigus and pemphigoid. When patient sera are incubated on monkey or guinea pig esophagus sections, anti-skin antibodies present in the serum will bind with disease-specific patterns by immunofluorescence. For example, the intercellular (IC) antibody pattern diagnoses pemphigus with a 90% sensitivity. Testing with the 2 different species of esophagus sections (monkey and guinea pig) assists in distinguishing different forms of pemphigus. Antibodies following a basement membrane pattern are present in bullous pemphigoid (70%), vesicular pemphigoid (50%) and cicatricial pemphigoid (10%).
  • Immune globulin G; Immunoglobulin G; Impression; Impression/interpretation of study; Impressions; Integument; Interp; Interpretation; Nominal; Point in time; Random; Serology; Serum; SR

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Skin Ab.IgG pattern Monkey esophagus substrate (S) [Interp]Skin Ab.IgG pattern [Interpretation] in Serum by Monkey esophagus substrateSkin Ab.IgG pattern Ser Monkey esoph-ImpSkin Ab.IgG patternSEROSkin Ab.IgG Pattern, BloodImp

Frequently asked questions

Code details

Code66880-6
SystemLOINC
Display nameSkin Ab.IgG pattern Monkey esophagus substrate (S) [Interp]
DescriptionSkin Ab.IgG pattern
Short nameSkin Ab.IgG pattern Ser Monkey esoph-Imp
ComponentSkin Ab.IgG pattern
PropertyImp
TimingPt
System (specimen)Ser
ScaleNom
MethodMonkey esophagus substrate
ClassSERO
StatusACTIVE
Order/ObservationObservation

Flags

BillableNo
Valid clinical useNo

Source

SourceLOINC
Version2.82
Releasemain
First released2.38
Last changed2.38

Consumer names

Skin Ab.IgG Pattern, Blood

Part names

Skin Ab.IgG patternImpPtSerNomMonkey esophagus substrateImpression/interpretation of studyPoint in time (spot)Serum

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

LOINC Code 66880-6 | HealthAssure