LOINC Code 68466-2: EBV-encoded RNA 1 Probe Ql (Tiss)

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component Epstein-Barr virus-encoded RNA 1. It is commonly used with the system or sample type Tiss.

When is it used?

• Used in lab systems, EHRs, and clinical data exchange.
• May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
• Status: ACTIVE
• Order vs observation: Both
• Method: Probe

What it does not mean

• The code identifies the observation or test, not the actual result.

Key facts

• Epstein-Barr virus-encoded RNA 1 [Presence] in Tissue by Probe
• Epstein-Barr virus-encoded RNA 1
• This term is used for the detection of nuclear Epstein-Barr virus-encoded RNA 1 (EBER1) by in situ hybridization on tissue. Presence of EBER1 indicates a latent EBV infection. EBV encodes two small nuclear RNAs, EBER1 and EBER2, which are the most abundant viral transcripts in latently infected cells. They are non-polyadenylated and thus not translated into protein. Their function is to inhibit interferon-mediated antiviral effects and apoptosis. Since they are expressed at high levels (around a million copies per latently infected cell), they are considered to be an ideal marker of latent EBV infection. In situ hybridization targeting one or both EBERs is used to determine whether a biopsied tumor is EBV-related.
• DNA NUCLEIC ACID PROBE; DNA probe; EBER; EBER1; EBV; EBV-encoded RNA1; Epstein-Barr virus; Epstn; HHV-4; human herpesvirus 4; i; ID; Infectious Disease; InfectiousDisease; Microbiology; Mono; Mononucleosis; Ordinal; Point in time; PR; QL; Qual; Qualitative; Random; Ribonucleic acid; Screen; Tissue; Tissue, unspecified

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Frequently asked questions