LOINC Code 71356-0: TPMT gene c.238G>C+460G>A+719A>G Molgen Nar (Bld/Tiss)

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component TPMT gene.c.238G>C+460G>A+719A>G. It is commonly used with the system or sample type Bld/Tiss.

When is it used?

• Used in lab systems, EHRs, and clinical data exchange.
• May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
• Status: ACTIVE
• Order vs observation: Both
• Method: Molgen

What it does not mean

• The code identifies the observation or test, not the actual result.

Key facts

• TPMT gene c.238G>C+460G>A+719A>G [Identifier] in Blood or Tissue by Molecular genetics method Narrative
• TPMT gene.c.238G>C+460G>A+719A>G
• Three main genetic polymorphisms [c.238G>C (rs1800462), c.460G>A (rs1800460), and c.719A>G (rs16880254)] in the TPMT gene alter metabolization efficiency of the thiopurines in 80-95% of patients. Patients with average TPMT activity are heterozygous for these genetic changes. Patients with deficient enzyme activity are homozygous for these polymorphisms. This code was created for, but not limited to, Asper Biotech's Thiopurine S-Methyltransferase Deficiency - TPMT test.
• Blood; Genetics; Heredity; Heritable; Identity or presence; Inherited; Molecular genetics; Molecular pathology; MOLPATH; MOLPATH.PHARMG; Narrative; PCR; Point in time; Random; Report; thiopurine S-methyltransferase; Thiopurine S-methyltransferase gene; Tissue; Tissue, unspecified; TPMT c.238G>C; TPMT c.238G>C+460G>A+719A>G; WB; Whole blood; Whole blood or Tissue

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Frequently asked questions