LOINC Code 72209-0: inv(16)(p13.1;q22.1)(MYH11,CBFB) fusion transcript/control transcript Molgen (BM) [# ratio]

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component inv(16)(p13.1;q22.1)(MYH11,CBFB) fusion transcript/control transcript. It is commonly used with the system or sample type Bone mar.

When is it used?

• Used in lab systems, EHRs, and clinical data exchange.
• May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
• Status: ACTIVE
• Order vs observation: Both
• Method: Molgen

What it does not mean

• The code identifies the observation or test, not the actual result.

Key facts

• inv(16)(p13.1;q22.1)(MYH11,CBFB) fusion transcript/control transcript [# Ratio] in Bone marrow by Molecular genetics method
• inv(16)(p13.1;q22.1)(MYH11,CBFB) fusion transcript/control transcript
• A pericentric inversion of chromosome 16, inv(16)(p13;q22), results in a fused transcript between MYH11 (16p13.1) and CBFB (16q22.1) genes and is known to cause acute myeloid leukemia (AML). Techniques like real-time PCR are used to detect the MYH11-CBFB fused transcript. An endogenous control gene transcript (e.g. ABL1, GUS or BCR) is amplified along with the fusion transcript of interest. Standard curves of known amounts of both the control and fusion transcript are used to calculate the ratio of the fusion transcript signal to the control gene signal.
• ABL; ABL1; ABL1 transcript; Acute myeloid leukemia; AML; BM; BON; Bone marrow; control gene; DNA; gene fusion; gene translocation; inv(16)(CBFB,MYH11) gene inversion; inv(16)(p13;q22); Inversion 16; MAR; Marrow (bone); minimal angle of resolution; Minimum angle of resolution; Molecular genetics; Molecular pathology; MOLPATH; MOLPATH.INV; Number ratio; PCR; Point in time; QNT; Quan; Quant; Quantitative; Random; RNA; translocation

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

Frequently asked questions