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LOINC Code 72212-4: t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 fusion transcript/control transcript Molgen (BM) [# ratio]

72212-4 is a LOINC code used to identify t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 fusion transcript/control transcript Molgen (BM) [# ratio] in laboratory and clinical observation data. You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges. LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 fusion transcript/control transcript. It is commonly used with the system or sample type Bone mar.

Reviewed by HealthAssure Clinical TeamUpdated 21 May 2026

What is this code?

LOINC codes identify tests, measurements, observations, survey items, and clinical questions in a standardized way. It is associated with the component t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 fusion transcript/control transcript. It is commonly used with the system or sample type Bone mar.

When is it used?

  • Used in lab systems, EHRs, and clinical data exchange.
  • May identify a test, observation, survey item, or clinical document request rather than a diagnosis.
  • Status: ACTIVE
  • Order vs observation: Both
  • Method: Molgen

What it does not mean

  • The code identifies the observation or test, not the actual result.

Key facts

t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 fusion transcript/control transcript [# Ratio] in Bone marrow by Molecular genetics method
t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 fusion transcript/control transcript
A balanced reciprocal translocation involving chromosomes 15 and 17, (15;17)(q22;q21), results in a fused transcript between PML and RARA genes. This gene fusion produces the PML-RARA fusion protein, a transcriptional repressor, which causes acute promyelocytic Leukemia (APL). Depending on the breakpoint within the PML gene, various fusion transcripts will be generatedlong (L or bcr1), variant (V or bcr2), and short (S or bcr3). Techniques like real-time PCR are used to detect the PML-RARA fused transcripts and breakpoints. An endogenous control gene transcript (e.g. ABL1, GUS or BCR) is amplified along with the fusion transcript of interest. Standard curves of known amounts of both the control and fusion transcript are used to calculate the ratio of the fusion transcript signal to the control gene signal.
ABL; ABL1; ABL1 transcript; Acute promyelocytic leukemia; APL; BM; BON; Bone marrow; breakpoint cluster region 1; control gene; DNA; gene fusion; gene translocation; Genetics; Heredity; Heritable; Inherited; long form; MAR; Marrow (bone); minimal angle of resolution; Minimum angle of resolution; Molecular genetics; Molecular pathology; MOLPATH; MOLPATH.TRANSLOCATION; Myelogenous; MYL; NR1B1; Number ratio; PCR; PML-1; PML-2; PML-3; PML-3B; PML-X; Point in time; Promyelocytic leukemia; QNT; Quan; Quant; Quantitative; Random; RAR alpha form; RARalpha; Retinoic acid receptor alpha; RNA; T prime; t(15,17) (PML,RARA) gene translocation; t(15,17)(PML,RARA) gene translocation breakpoint cluster region 1; t(15,17)(q22,q11.2-q12); t(15;17) BCR1; t(15;17)(PML,RARA); translocation

Where you may see this code

You may see this code in lab systems, lab reports, EHR exports, interoperability feeds, or other structured clinical data exchanges.

Common synonyms

t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 fusion transcript/control transcript Molgen (BM) [# ratio]t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 fusion transcript/control transcript [# Ratio] in Bone marrow by Molecular genetics methodt(15;17) BCR1/control Mart(15;17)(q24.1;q21.1)(PML,RARA) bcr1 fusion transcript/control transcriptMOLPATH.TRNLOCt(15;17)(q24.1;q21.1)(PML,RARA) Bcr1/control Transcript, Bone marrowNRto

Frequently asked questions

Code details

Code72212-4
SystemLOINC
Display namet(15;17)(q24.1;q21.1)(PML,RARA) bcr1 fusion transcript/control transcript Molgen (BM) [# ratio]
Descriptiont(15;17)(q24.1;q21.1)(PML,RARA) bcr1 fusion transcript/control transcript
Short namet(15;17) BCR1/control Mar
Componentt(15;17)(q24.1;q21.1)(PML,RARA) bcr1 fusion transcript/control transcript
PropertyNRto
TimingPt
System (specimen)Bone mar
ScaleQn
MethodMolgen
ClassMOLPATH.TRNLOC
Example units%
StatusACTIVE
Order/ObservationBoth

Flags

BillableNo
Valid clinical useNo

Source

SourceLOINC
Version2.82
Releasemain
First released2.42
Last changed2.42

Consumer names

t(15;17)(q24.1;q21.1)(PML,RARA) Bcr1/control Transcript, Bone marrow

Part names

t(15;17)(q24.1;q21.1)(PML,RARA) bcr1 fusion transcript/control transcriptNRtoPtBone marQnMolgenNumber RatioPoint in time (spot)Bone marrowMolecular genetics

About this content

This page is prepared by HealthAssure's clinical team using official coding standards from LOINC. AI tools assist with drafting explanations, which are then reviewed and verified by healthcare professionals for accuracy. This content is for informational purposes and does not replace professional medical advice. Meet our team.

LOINC Code 72212-4 | HealthAssure